DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and CLIPA9

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_309727.4	Gene:	CLIPA9 / 1270989	VectorBaseID:	AGAP010968	Length:	361	Species:	Anopheles gambiae

Alignment Length:	282	Identity:	86/282 - (30%)
Similarity:	127/282 - (45%)	Gaps:	37/282 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 CGSAFSFRLVGGHNTGLF-----EFPWTTLLEYETVSGGK---DYACGASFIAQRWLLTAAHCIH 180
            |||..:|.||....:.|.     |||||..:...:.|..:   ....|.|.|..:::|||||.:.
Mosquito    94 CGSPVTFPLVYNVESNLTYANYGEFPWTVAIFNISFSANEMKLTLVGGGSLIHPKFVLTAAHTLK 158

  Fly   181 TMGRNLTAAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSE-LNYRNDIALLRL 244
            ...|.:  |..|||:.::|.:..           |...:.|:..:.|..|.: ....|||||..|
Mosquito   159 KPDRYV--ARFGEWSINSDAEIY-----------PSQDIGIEEHIIHPSYRDSCLLENDIALAVL 210

  Fly   245 SRPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWG-KTESSGSSKIKQKAMLHIQPQDQCQ 308
            .|  |.:..:::.|:|||..    .:...|.....:||| ...:...:.|.::..|.:.|:|:||
Mosquito   211 KR--NVIYTEHIRPICLPSP----TDVFDGQRCIATGWGLDVRTQQPAPIMKRIELPVVPRDRCQ 269

  Fly   309 EAFYK---DTKITLADSQMCAGGEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCG 370
            ..:.:   |....|..|.||||||:|.|:|..|.|.||..:....|   || :||:.|.| ..||
Mosquito   270 LLYRRAEVDYSFKLHRSMMCAGGEVGEDTCDQDGGTPLACKKEDGS---YV-VAGITSWG-LDCG 329

  Fly   371 TALFSGIYTRVSSYMDWIESTI 392
            .....|||..|:.:..||..||
Mosquito   330 RVDAPGIYVDVAKFACWINDTI 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	78/269 (29%)
		Tryp_SPc	133..391	CDD:238113	79/270 (29%)
CLIPA9	XP_309727.4	Tryp_SPc	113..350	CDD:238113	77/260 (30%)
CLIPA9	XP_309727.4	Tryp_SPc	113..347	CDD:214473	75/257 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910