DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and AgaP_AGAP011325

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_309327.4	Gene:	AgaP_AGAP011325 / 1270612	VectorBaseID:	AGAP011325	Length:	631	Species:	Anopheles gambiae

Alignment Length:	322	Identity:	111/322 - (34%)
Similarity:	160/322 - (49%)	Gaps:	53/322 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 VCCPRETNIIPPLAPRISNGTTNATSSTTTLKLLPRTTPRPPSGIDQLPEHPYCGSAFSFRLVGG 135
            |||.:|.:            :.|......||..|.:                 ||.....::..|
Mosquito   353 VCCQQEAD------------SNNHRKRNLTLLDLEK-----------------CGPYIEEKIANG 388

  Fly   136 HNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTAAILGEWNRDTDP 200
            .:..||::||..||:...::    :.||.:.|.:|::||||||.......::.. |||::..:|.
Mosquito   389 IDAILFQYPWMALLQDTELA----FVCGGTLINKRYVLTAAHCFREKLSKISVR-LGEFDLKSDI 448

  Fly   201 DCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQNLEPVCLP--P 263
            ||  |..|.| ||.|...:.::|.:.|..||..:..|||||:||:...::  .:|:.|:|||  |
Mosquito   449 DC--DKRGER-CALPPQDIAVERTIKHKDYSARHKVNDIALIRLASEASY--NENVMPICLPVSP 508

  Fly   264 QRGRYANQLAGSAADVSGWGKTESSGSSKIKQKAMLHIQPQDQCQEAFY-KDTKITLADSQMCAG 327
            :. |...::    ..|||||.||:..||.:.|..:|...|.|.||:... ||..:|:...||||.
Mosquito   509 EM-RTVKEI----YYVSGWGLTENDTSSDVLQVGLLRQLPNDVCQQLLQRKDKYVTVNSDQMCAI 568

  Fly   328 GEIGVDSCSGDSGGPL-TVEANTASGNRYVYLAGVVSIGRKHCGTALFSGIYTRVSSYMDWI 388
            |....|:||||||||| ||..|.    |:|.. ||||.|.:.||.....|:||||.:|:|||
Mosquito   569 GANRTDNCSGDSGGPLKTVAVNA----RFVQY-GVVSYGLRTCGKETAPGVYTRVENYIDWI 625

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829	2/2 (100%)
		Tryp_SPc	131..388	CDD:214473	99/260 (38%)
		Tryp_SPc	133..391	CDD:238113	101/260 (39%)
AgaP_AGAP011325	XP_309327.4	Tryp_SPc	44..287	CDD:238113
		Tryp_SPc	46..286	CDD:214473
		Tryp_SPc	384..625	CDD:214473	99/260 (38%)
		Tryp_SPc	385..625	CDD:238113	99/259 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920