DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and AgaP_AGAP007043

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_001237132.2	Gene:	AgaP_AGAP007043 / 1270058	VectorBaseID:	AGAP007043	Length:	575	Species:	Anopheles gambiae

Alignment Length:	262	Identity:	75/262 - (28%)
Similarity:	114/262 - (43%)	Gaps:	35/262 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   142 EFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRN---LTAAILGEWNRDTDPDCE 203
            ::||...|.....|....|.||.|.|:|.::|:|||||.....:   |.|.| ...|.|.|...
Mosquito    57 DWPWHVALFAHMKSEKPAYKCGGSIISQHFVLSAAHCIKEPNPDHYFLKAGI-HHLNNDNDTSV- 119

  Fly   204 NDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQNLEPVCLPPQRGRY 268
                         :...:..|:.|.:|....:.|||||:|..|.:::... ::.|:||.|.....
Mosquito   120 -------------VVYNLFEIILHPKYDRHTFYNDIALMRPDRAISFASF-SIFPICLWPTHNAT 170

  Fly   269 ANQLAGSAADVSGWGKTESSGSSKIKQKAMLHIQPQDQCQEAFYKDTKITLADS-QMCA-GGEIG 331
            ...:...:....|:|..|:...|:..|:|.:.:..:.||.|...:..:....|: :||| |.|.|
Mosquito   171 LIDVLSRSGIAVGFGFDETHRISETLQQASMKVIEKQQCIEQLPEHVRFLPQDAGKMCAIGTESG 235

  Fly   332 VDSCSGDSGGPLTVEANTASGNRYVYLAGVVS--------IGRKHCGTALFSGIYTRVSSYMDWI 388
            .:.|||||||.|..     :.::..||.|:||        .|...|..|| ...||.|:.|..||
Mosquito   236 ANVCSGDSGGGLYF-----AKDQVWYLRGIVSAAARRDLDTGEATCNAAL-PATYTDVAQYTTWI 294

  Fly   389 ES 390
            .:
Mosquito   295 NA 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	73/258 (28%)
		Tryp_SPc	133..391	CDD:238113	75/262 (29%)
AgaP_AGAP007043	XP_001237132.2	Tryp_SPc	50..297	CDD:238113	75/262 (29%)
		Tryp_SPc	50..294	CDD:214473	73/258 (28%)
		Tryp_SPc	330..573	CDD:304450
		Tryp_SPc	330..570	CDD:214473
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910