DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and AgaP_AGAP007280

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_308537.4	Gene:	AgaP_AGAP007280 / 1269883	VectorBaseID:	AGAP007280	Length:	2275	Species:	Anopheles gambiae

Alignment Length:	279	Identity:	79/279 - (28%)
Similarity:	125/279 - (44%)	Gaps:	49/279 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   129 SFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTAAILGE 193
            |.|:|||.:.....:|:...:    ...|| |.||.|...:.|:::||||.....::......|.
Mosquito   939 SVRIVGGSHADPEAYPFIVGI----FRDGK-YHCGGSIYNEHWIISAAHCCDNFDQHYFEVRSGM 998

  Fly   194 WNRDTDPDCENDLNGVRECAPPHIRVT-IDRILPHAQYSELNYRNDIALLRLSRPVN---WLQMQ 254
            ..:             |..| |.:::| :..::.|..||.....|||||:|:..|.:   |::
Mosquito   999 LRK-------------RSFA-PQVQITRVTHMIVHHAYSSSLMANDIALMRVEHPFHYNRWVR-- 1047

  Fly   255 NLEPVCLPPQRGRYANQ-------LAGSAADVSGWGKTESSGSSKIKQKAMLHIQPQDQCQEAFY 312
               |:|: |:|.|..:.       .||:.....|||.....|.:. .....:.:.....|:....
Mosquito  1048 ---PICM-PERHRTTDDRDWIWGPKAGTVCTAIGWGALRERGGAP-DHLMQVSVPILGYCKHKSD 1107

  Fly   313 KDTKITLADSQMCAGGEI-GVDSCSGDSGGPLTVEANTASGNRYV-YLAGVVSIGRKHCGTALFS 375
            :|:      .|:||..|. |.|:|.||||||...::.:   |.:. |||||||.| :.|..|...
Mosquito  1108 RDS------LQICAAEEDGGHDACQGDSGGPFVCQSKS---NPFEWYLAGVVSHG-EGCARAHEP 1162

  Fly   376 GIYTRVSSYMDWIESTIRA 394
            |:||||:.::|||...:.|
Mosquito  1163 GVYTRVALFIDWIAEKVNA 1181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	75/269 (28%)
		Tryp_SPc	133..391	CDD:238113	76/270 (28%)
AgaP_AGAP007280	XP_308537.4	LDLa	698..733	CDD:238060
		Tryp_SPc	941..1175	CDD:214473	75/269 (28%)
		Tryp_SPc	942..1178	CDD:238113	76/271 (28%)
		LDLa	1196..1226	CDD:238060
		LDLa	1510..1541	CDD:238060
		LDLa	1574..1609	CDD:238060
		DUF1986	1774..1887	CDD:286432
		LDLa	1999..2025	CDD:238060
		LDLa	2038..2071	CDD:238060
		LDLa	2107..2142	CDD:238060
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910