DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and AgaP_AGAP010635

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_307830.4	Gene:	AgaP_AGAP010635 / 1269219	VectorBaseID:	AGAP010635	Length:	569	Species:	Anopheles gambiae

Alignment Length:	305	Identity:	86/305 - (28%)
Similarity:	131/305 - (42%)	Gaps:	57/305 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   116 DQLPEHPY----CGSAFSFRLV-------GGHNTGLFEFPWTTLLEYETVSGGKD--YACGASFI 167
            |:|..:.|    ||.    |||       ||::|...::||...| |......:|  ||||::.:
Mosquito    25 DELEIYDYNDNECGE----RLVKRQELVKGGYSTHPGDWPWHAAL-YHRGFNSRDFEYACGSTIV 84

  Fly   168 AQRWLLTAAHCI--HTMGRNLTA----AILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILP 226
            .:..::|||||:  .|..|.:.:    ..||.:|.         :|...|.|...  ..||.|:
Mosquito    85 HRYLVITAAHCVTFATSRRKIPSDNMQLRLGRFNL---------MNNEEEYAEEF--SVIDTIV- 137

  Fly   227 HAQYSELNYRNDIALLRLSRPVNWLQMQNLEPVCL-PPQRGRYANQLAGSAADVSGWGKTESSGS 290
            |..|......||||:||:..|:  :....::|||| ....|.....:......|.|||.:|::..
Mosquito   138 HEGYRPTTLENDIAILRVEIPI--IFNDYIQPVCLWKRDDGFDLPNVYNQPGTVVGWGLSENNRI 200

  Fly   291 SKIKQKAMLHIQPQDQC---QEAFYKDTKITLADSQMCAGGEIGVDSCSGDSGGPLTVEANTASG 352
            .....:|.:.:.....|   ..||:..   .|.....|||.:.|...|:|||||.:..:..
Mosquito   201 GTTLNEAQMPVVNSWTCLASDRAFFGR---FLQSKAFCAGYKNGTGVCNGDSGGGMFFQFQ---- 258

  Fly   353 NRYVYLAGVVSIGRKH-----CGTALFSGIYTRVSSYMDWI-EST 391
            ||: ||.|:||....:     |....:.| :|..|.|:||: |:|
Mosquito   259 NRW-YLKGIVSFSSVNDYSGWCNLRQYIG-FTDASQYIDWVYENT 301

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	78/280 (28%)
		Tryp_SPc	133..391	CDD:238113	78/282 (28%)
AgaP_AGAP010635	XP_307830.4	Tryp_SPc	50..300	CDD:238113	76/273 (28%)
		Tryp_SPc	50..297	CDD:214473	75/270 (28%)
		Tryp_SPc	342..563	CDD:214473
		Tryp_SPc	342..563	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910