DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and CLIPB4

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_307755.1	Gene:	CLIPB4 / 1269159	VectorBaseID:	AGAP003250	Length:	360	Species:	Anopheles gambiae

Alignment Length:	406	Identity:	136/406 - (33%)
Similarity:	200/406 - (49%)	Gaps:	71/406 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LLIPLFLTLLGAE--AQQFGKAIMHFGNCNSVEFGRGTCIEKKDC----DFYAVDKLM------E 55
            |||...|.|.|..  |.:.|:      :|.:.....|.|:..::|    |.|  :|.:      :
Mosquito     9 LLIVATLALAGQTVLALELGQ------DCVNPVGEAGKCVLFRECQPLVDIY--NKPVNTPDDTQ 65

  Fly    56 LASKQQCFSRQRPDLVCCPRETNIIPPLAPRISNGTTNATSSTTTLKLLPRTTPRPPSGIDQLPE 120
            ..::.:|...:|..||||          |...|.|.|:                        |||
Mosquito    66 FLTESRCGLYERKTLVCC----------AGVRSKGKTS------------------------LPE 96

  Fly   121 HPYCGSAFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTM--G 183
            .|.||...:.|::||..|.:.|||||.|:|||..:|...:.||.|.|.:|::|||||||.::  |
Mosquito    97 SPNCGVQLTDRVIGGQPTKIDEFPWTALIEYEKPNGRFGFHCGGSVINERYILTAAHCITSIPRG 161

  Fly   184 RNLTAAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYS--ELNYRNDIALLRLSR 246
            ..:....||||:..:..|.|:|.     .|...|.:.|::|:.|..|:  :.::.|||||:|.:|
Mosquito   162 WKVHRVRLGEWDLSSTTDQEDDF-----YADAPIDLDIEKIIVHPGYNLQDKSHHNDIALIRFNR 221

  Fly   247 PVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSGSSKIKQKAMLHIQPQDQCQEAF 311
            .:|:  ...:..:|||........:.||.::..:||||||::.:|:.|.|..|.:.....|..|
Mosquito   222 EINY--SSTISAICLPLSNSLRNRKHAGLSSYAAGWGKTETASASQKKLKVELTVVDVKDCSPA- 283

  Fly   312 YKDTKITLADSQMCAGGEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSG 376
            |:...|:|..:||||||..|.|:|||||||||   ....||:  .||.||||.|.:.||.....|
Mosquito   284 YQRNGISLDSTQMCAGGIRGKDTCSGDSGGPL---MRQMSGS--WYLIGVVSFGPQKCGAPGVPG 343

  Fly   377 IYTRVSSYMDWIESTI 392
            :||.|:.|:|||:..|
Mosquito   344 VYTNVAEYVDWIKDNI 359

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829	12/54 (22%)
		Tryp_SPc	131..388	CDD:214473	102/260 (39%)
		Tryp_SPc	133..391	CDD:238113	103/261 (39%)
CLIPB4	XP_307755.1	CLIP	31..83	CDD:371857	11/53 (21%)
CLIPB4	XP_307755.1	Tryp_SPc	108..358	CDD:238113	103/262 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	3	2.880