DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Gzmbl3

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_001316809.1	Gene:	Gzmbl3 / 120766154	RGDID:	2320502	Length:	248	Species:	Rattus norvegicus

Alignment Length:	264	Identity:	76/264 - (28%)
Similarity:	123/264 - (46%)	Gaps:	40/264 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   132 LVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTAAILGEWNR 196
            ::|||.......|:...|:......|.. .||...|.:.::||||||   :|..:|.. ||..|
  Rat    21 IIGGHEAKPHSRPYMAYLQIMDEDSGST-MCGGFLIQEDFVLTAAHC---LGSKITVT-LGAHN- 79

  Fly   197 DTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQNLEPVCL 261
                        ::|.......:.:.:|:||..|:...|.|||.||:|.....  :.:.::.:.|
  Rat    80 ------------IKEQEKMQQVIPVVKIIPHPAYNSKKYSNDIMLLKLKSKAK--RTRAVKTLSL 130

  Fly   262 PPQRGRYANQLAGSAADVSGWGKTESSGSSKIK-QKAMLHIQPQDQCQEAFYKDTKITLADSQMC 325
            |  |..:..: .|...:|:||||....|....| |:..|.:|...:| |.::|  |.....:|:|
  Rat   131 P--RSNFKVK-PGDVCNVAGWGKLGPMGKFPDKLQEVELTVQEDQEC-ETYFK--KAYNKANQIC 189

  Fly   326 AGG-EIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSGIYTRVSSYMDWIE 389
            ||. :|...|..|||||||..:.         ..||:|:.|.|: |:|  ...:|:||:::.||:
  Rat   190 AGDPKIKRASFGGDSGGPLVCKK---------VAAGIVAYGSKN-GSA--PEAFTKVSTFLSWIK 242

  Fly   390 STIR 393
            .|::
  Rat   243 ETMK 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	73/257 (28%)
		Tryp_SPc	133..391	CDD:238113	75/259 (29%)
Gzmbl3	NP_001316809.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910