DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and CTRC

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_011538852.1	Gene:	CTRC / 11330	HGNCID:	2523	Length:	280	Species:	Homo sapiens

Alignment Length:	171	Identity:	49/171 - (28%)
Similarity:	76/171 - (44%)	Gaps:	26/171 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   114 GIDQLPEHPYCGSAFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHC 178
            |:...|.:      .|.|:|||.:.....:||...|:|......: :.||.:.||..::||||||
Human    18 GVPSFPPN------LSARVVGGEDARPHSWPWQISLQYLKNDTWR-HTCGGTLIASNFVLTAAHC 75

  Fly   179 IHTMGRNLTAAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLR 243
            |... |....|: |:.|.:.: |.|..|           .|.:|.|..|.:::.|..||||||::
Human    76 ISNT-RTYRVAV-GKNNLEVE-DEEGSL-----------FVGVDTIHVHKRWNALLLRNDIALIK 126

  Fly   244 LSRPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGK 284
            |:..|.  ....::..|||.:........   ...|:|||:
Human   127 LAEHVE--LSDTIQVACLPEKDSLLPKDY---PCYVTGWGR 162

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	46/154 (30%)
		Tryp_SPc	133..391	CDD:238113	45/152 (30%)
CTRC	XP_011538852.1	Tryp_SPc	29..>163	CDD:214473	46/154 (30%)
CTRC	XP_011538852.1	Tryp_SPc	30..>173	CDD:238113	45/153 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910