DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and AgaP_AGAP013020

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_003435910.1	Gene:	AgaP_AGAP013020 / 11175979	VectorBaseID:	AGAP013020	Length:	454	Species:	Anopheles gambiae

Alignment Length:	353	Identity:	90/353 - (25%)
Similarity:	145/353 - (41%)	Gaps:	62/353 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    78 NIIPP-LAPRISNGTTNATSS-----TTTLKLLPRTTPRPPSGID------------QLPEHPY- 123
            ||.|. ||.|::..|..|...     .||:.|.....|...|.:.            |.|:.|.
Mosquito   127 NIKPSVLAIRVNGHTICAGQKVTGQIVTTINLQHTLYPSTQSLVSTNDGTNVNVIQYQPPQTPVD 191

  Fly   124 CG---SAFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHT---M 182
            ||   ..||...:.|.:.....|||...:.:...|....|.||::.:.:|.|:|||||::.   :
Mosquito   192 CGLPDKGFSHYSINGVHAHKGMFPWAAPIFHTGSSSKPRYICGSTILTERHLVTAAHCVYNSDGI 256

  Fly   183 GRNLT--AAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLS 245
            .:|::  ..:.|..|.|...:.:....||::     |.|..|....|....:.    |||:|.|.
Mosquito   257 KQNVSDLTVVPGMHNIDNFFEADLQERGVKK-----IFVHNDYFFEHGMLVDA----DIAVLLLD 312

  Fly   246 RPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSGSSKIKQKAMLHIQPQDQC--- 307
            .|:.:.::  :.|:|:...... ..::.|....|||||.|| .|.:||....|..:..:..|
Mosquito   313 DPITYNKL--VRPICMWSDSDN-LEKIVGDEGFVSGWGVTE-DGKAKIPSYVMATVVDRQTCNRN 373

  Fly   308 -QEAFYKDTKITLADSQMCAGGEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGR----- 366
             ...|....:|      .||.|. |...|:||||....::    .|.|| |:.|:||.|:
Mosquito   374 LDRLFAAKARI------FCADGH-GSVPCTGDSGSGFVIK----RGPRY-YIRGIVSFGQFDPKT 426

  Fly   367 KHCGTALFSGIYTRVSSYMDWIESTIRA 394
            ..|.|..:. :||.::.:..|:...:::
Mosquito   427 LTCATDKYV-VYTDIAPFRYWLTRVMKS 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	69/270 (26%)
		Tryp_SPc	133..391	CDD:238113	70/271 (26%)
AgaP_AGAP013020	XP_003435910.1	GD_N	46..146	CDD:292649	8/18 (44%)
		Tryp_SPc	204..450	CDD:238113	70/271 (26%)
		Tryp_SPc	204..446	CDD:214473	69/267 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910