DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and AgaP_AGAP013089

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_003436251.1	Gene:	AgaP_AGAP013089 / 11175918	VectorBaseID:	AGAP013089	Length:	634	Species:	Anopheles gambiae

Alignment Length:	411	Identity:	122/411 - (29%)
Similarity:	189/411 - (45%)	Gaps:	73/411 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 NCNSVEFGRGTCIEKKDCDFYAV---------DKLME-LASKQQCFSRQRPDLVCCP------RE 76
            :|.:.....|.||...:|||...         |..:| ..::..|.......:||||      ::
Mosquito   249 SCLTPNAQNGICIVYVNCDFILQLLIRNANLRDPAIENYVAQSVCGYSDVTPMVCCPTFRFAHQD 313

  Fly    77 TNII-----PP----------LAPRISNGTTNATSSTTTLKLLPRTTPRPPSGIDQLPEHPY--C 124
            :|..     ||          .|...|:|..::|:..||:      || ..:|.::||.:..  |
Mosquito   314 SNTTSSFTNPPTVTTAPGSFFFAAVSSSGAGSSTAGPTTV------TP-SSTGSNRLPTNDVDRC 371

  Fly   125 G--SAFSFRLVGGHNTGLFEFPWTTLLEYETVS----GGKDYACGASFIAQRWLLTAAHCIHTMG 183
            |  :....|:|||.:..|..:||...|.|.:.|    .|..:.||.:.|....:||.||||.|.
Mosquito   372 GMSNGTHTRVVGGVDAQLNAWPWMAALGYRSTSFELNAGPRFLCGGTLITTLHVLTVAHCIQTA- 435

  Fly   184 RNLTAAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPV 248
              |....|||.:..:|.|..|.::           :.|.|.:.|.:|.|....|||||:.|.:.|
Mosquito   436 --LYFVRLGELDITSDQDGANPVD-----------IYIQRWVVHERYDEKKIYNDIALVLLQKSV 487

  Fly   249 NWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSGSSKIK-QKAMLHIQPQDQCQEAF- 311
            ...:.  :.|:|||.:..:....|...|..::|||....:|.:..: |:|.:.:.|.|||  ||
Mosquito   488 TITEA--VRPICLPVEAKQRTKDLTYYAPFIAGWGAVGYNGPTAARLQEAQVVVLPVDQC--AFN 548

  Fly   312 ---YKDTKITLADSQMCAG-GEIGVDSCSGDSGGPLTVEANTASGNRYVY-LAGVVSIGRKHCGT 371
               |...:| ..|:.:||| .:.|.|||.|||||||.:...:::|..|.| |.|::|.|.: |..
Mosquito   549 YKLYFPGQI-FDDTVLCAGFPQGGKDSCQGDSGGPLMLPELSSNGQYYYYTLIGLISYGYE-CAR 611

  Fly   372 ALFSGIYTRVSSYMDWIESTI 392
            |.|.|:|.:|::|:.|||:.:
Mosquito   612 AGFPGVYVKVTAYLPWIEANL 632

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829	12/54 (22%)
		Tryp_SPc	131..388	CDD:214473	89/267 (33%)
		Tryp_SPc	133..391	CDD:238113	91/268 (34%)
AgaP_AGAP013089	XP_003436251.1	CLIP	250..304	CDD:288855	11/53 (21%)
		Tryp_SPc	380..628	CDD:214473	89/267 (33%)
		Tryp_SPc	381..631	CDD:238113	91/269 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920