DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and Prss48

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_017446782.1	Gene:	Prss48 / 108350052	RGDID:	11436036	Length:	308	Species:	Rattus norvegicus

Alignment Length:	280	Identity:	86/280 - (30%)
Similarity:	128/280 - (45%)	Gaps:	46/280 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 CG-SAFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCI-HTMGRNL 186
            || ..:|.|:|||....|..:||...|.:::.     :.||.|.|:..|::|||||| .|....|
  Rat    31 CGRPVYSGRIVGGQGAALGHWPWQVSLRFDST-----HICGGSLISNHWVMTAAHCIKKTWFSFL 90

  Fly   187 TAAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWL 251
            .:..||..:||.....|              ...:.||:..:::.  |...|||||:||..|.:.
  Rat    91 YSVWLGSIDRDYSSTGE--------------EYYVSRIVIPSKHH--NTDGDIALLKLSSRVTFT 139

  Fly   252 QMQNLEPVCLPPQRGRYANQLAGSAAD-VSGWGKTESSGSSKIKQKAMLHIQPQDQCQEA----- 310
            .:  :.|:|||    ..:..|...|:. |:|||:.:........|:..:.|...:.|::.
  Rat   140 SL--VLPICLP----NISKPLTVPASCWVTGWGQNQEGHYPSTLQELEVPIITGEACEQLYNPIG 198

  Fly   311 -FYKDTKITLADSQMCAGGEI--GVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTA 372
             |..|.:..:.:..:|| |||  ..|||.|||||||:...:.....     .||:|.|.: ||..
  Rat   199 FFLPDLERIIKEDMLCA-GEIQQSKDSCKGDSGGPLSCHIDGVWTQ-----IGVISWGLE-CGKN 256

  Fly   373 LFSGIYTRVSSYMDWIESTI 392
            | .|:||.|:.|..||.|.|
  Rat   257 L-PGVYTNVTYYQKWISSII 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	79/266 (30%)
		Tryp_SPc	133..391	CDD:238113	80/267 (30%)
Prss48	XP_017446782.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910