DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and si:dkey-32n7.7

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_021335883.1	Gene:	si:dkey-32n7.7 / 108191692	ZFINID:	ZDB-GENE-121214-179	Length:	609	Species:	Danio rerio

Alignment Length:	382	Identity:	107/382 - (28%)
Similarity:	153/382 - (40%)	Gaps:	122/382 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 GKAIMHFGNCNSVEFGRGTCIEKKDCDFYAVDKLMELASKQQCFSRQRPDLVCCPRETNIIPPLA 84
            |:.:....|.:.|   :|:||   :.:..|:|.               |....|    .|||
Zfish   265 GRWVFRVDNSSEV---KGSCI---NTNSQALDS---------------PSAAVC----GIIP--- 301

  Fly    85 PRISNGTTNATSSTTTLKLLPRTTPRPPSGIDQLPEHPYCGSAFSFRLVGGHNTGLFEFPWTTLL 149
            ...||||                                         |||.|:....:||...|
Zfish   302 VNSSNGT-----------------------------------------VGGQNSSAVHWPWQASL 325

  Fly   150 EYETVSGGKDYACGASFIAQRWLLTAAHCIHTM--GRNLTAAILGEWNRDTDPDCENDLNGVREC 212
            .:  .||   ..||.|.|.:.|:|:||||.:..  |..|| .|||       |..:|..:
Zfish   326 YW--YSG---QTCGGSLINKEWVLSAAHCFNGQRNGFYLT-VILG-------PKTQNKYD----- 372

  Fly   213 APPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQNLEPVCLPPQRGRYANQLAGSA- 276
             |..|..::..::.|..|:.....|||||:|||.|:.:  ..::.||||..:         ||.
Zfish   373 -PSRISRSVKAVIKHPYYNPNTNDNDIALVRLSFPITF--TDSIRPVCLAAE---------GSVF 425

  Fly   277 -ADVSGW---GKTESSG----SSKIKQKAMLHIQPQDQCQEAFYKDTKITLADSQMCAG-GEIGV 332
             :|...|   .:..|.|    |.||.|:..:.:....|| ...|....||  |:.:||| .:.|.
Zfish   426 NSDTESWITTWRNISDGVPLPSPKIFQEVEVPVIGNRQC-NCLYGVGSIT--DNMICAGLLKEGK 487

  Fly   333 DSCSGDSGGPLTVEANTASGNRYVYL-AGVVSIGRKHCGTALFSGIYTRVSSYMDWI 388
            |.|.||||||:.  :|.:|    |:: :|:||.| ..|..:.|.|:|||||.|.:||
Zfish   488 DLCQGDSGGPMV--SNQSS----VWVQSGIVSFG-SGCAQSEFPGVYTRVSRYQEWI 537

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829	7/44 (16%)
		Tryp_SPc	131..388	CDD:214473	88/269 (33%)
		Tryp_SPc	133..391	CDD:238113	90/269 (33%)
si:dkey-32n7.7	XP_021335883.1	NIDO	4..63	CDD:310601
		NIDO	141..272	CDD:322035	1/6 (17%)
		Tryp_SPc	309..537	CDD:238113	88/267 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910