DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ser7 and LOC101732176

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_031752403.1	Gene:	LOC101732176 / 101732176	-ID:	-	Length:	516	Species:	Xenopus tropicalis

Alignment Length:	342	Identity:	94/342 - (27%)
Similarity:	132/342 - (38%)	Gaps:	94/342 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 SNGTTNATSSTTTLKLLPRTTPRPPSGIDQLPEHPYC--GSAFSF-------------RLVGGHN 137
            |||.....|||.|.||           ...|.....|  |:..|.             |:|||..
Frog   229 SNGYVKLKSSTVTGKL-----------YKNLQYSATCTTGTMVSLRCINCGLSTKVDNRIVGGTF 282

  Fly   138 TGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIH----------------TMGRNL 186
            ....::||.  :....:.|...|.||.|.|...|::|||||::                |:....
Frog   283 ALAGDWPWQ--ISLMKLVGTSLYLCGGSIITPYWIVTAAHCVYGYTSSPSIFKVFAGSLTLSNYY 345

  Fly   187 TAAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWL 251
            :|..|                             :||:|.|..||......|||||:|...:  :
Frog   346 SAGYL-----------------------------VDRVLIHPSYSPNTQNYDIALLKLKTAL--V 379

  Fly   252 QMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSGSSKIKQK-AMLHIQPQDQCQEA-FYKD 314
            ...||.|||||.....:|:   |....:||||.|..:||.....| |.:.|.....|..| .|..
Frog   380 FSTNLRPVCLPNVGMPWAD---GQPCWISGWGTTSEAGSISTSLKAASVPIISSATCNLAPVYGG 441

  Fly   315 TKITLADSQMCA---GGEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSG 376
               .::.:.:||   ||  |.|:|.|||||||..:.|:     ..:|.|..|.| ..|..|...|
Frog   442 ---VISPTMICAGYLGG--GTDTCQGDSGGPLVTKTNS-----LWWLVGDTSWG-YGCARAYKPG 495

  Fly   377 IYTRVSSYMDWIESTIR 393
            :|..::.:::||.|.::
Frog   496 VYGNITVFLEWIYSQMQ 512

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	78/277 (28%)
		Tryp_SPc	133..391	CDD:238113	79/278 (28%)
LOC101732176	XP_031752403.1	LDLa	<115..133	CDD:238060
		LDLa	140..171	CDD:238060
		SRCR_2	176..271	CDD:406055	13/52 (25%)
		Tryp_SPc	277..510	CDD:238113	79/279 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910