DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and cela1.2

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_001307331.1	Gene:	cela1.2 / 100535584	ZFINID:	ZDB-GENE-050208-732	Length:	269	Species:	Danio rerio

Alignment Length:	274	Identity:	78/274 - (28%)
Similarity:	126/274 - (45%)	Gaps:	40/274 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   127 AFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTAAIL 191
            |...|:|||.......:||...|:|..: |...|.|..:.|...|::.||||:..: |..|.| |
Zfish    25 AIEERVVGGEIAKPHSWPWQISLQYSDL-GTYYYYCSGTLIRPGWVMVAAHCVEAL-RKWTVA-L 86

  Fly   192 GEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELN--YRNDIALLRLSRPV---NWL 251
            |:.:..|...             |...:::..:..|..::..|  :..||||||||...   :::
Zfish    87 GDHDIYTHEG-------------PEQYISVSEVFIHPNWNPNNVAFGYDIALLRLSIDATLSSYV 138

  Fly   252 QMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSG--SSKIKQKAMLHIQPQDQCQEAFYKD 314
            |:..|      |..|.....  |....::|||.||:.|  |:::|| |.:.:...:.|.:..:..
Zfish   139 QVATL------PSSGEILPY--GHTCYITGWGYTETGGSLSAQLKQ-AYMPVVDYETCSQKDWWG 194

  Fly   315 TKITLADSQMCAGGEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVS-IGRKHCGTALFSGIY 378
            :.:  .::.:||||...:.:|.||||.||    |.....:|| :.||.| :..:.|.|......:
Zfish   195 SSV--KETMICAGGTTSMSACHGDSGSPL----NCLFNGKYV-VHGVTSFVSPEGCNTYKKPTGF 252

  Fly   379 TRVSSYMDWIESTI 392
            ||||:|::||...|
Zfish   253 TRVSAYINWINQII 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	74/264 (28%)
		Tryp_SPc	133..391	CDD:238113	75/265 (28%)
cela1.2	NP_001307331.1	Tryp_SPc	29..262	CDD:214473	74/264 (28%)
cela1.2	NP_001307331.1	Tryp_SPc	30..265	CDD:238113	75/266 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910