DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and mst1

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_004915630.2	Gene:	mst1 / 100494056	XenbaseID:	XB-GENE-487985	Length:	736	Species:	Xenopus tropicalis

Alignment Length:	280	Identity:	78/280 - (27%)
Similarity:	128/280 - (45%)	Gaps:	48/280 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 CG-----SAFSFRLVGG--HNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHT 181
            ||     |:...|:|||  .|:     |||..|.    :...::.||.|.:.:.|:::...|..:
Frog   493 CGKRNDRSSQRTRIVGGMPGNS-----PWTVSLR----NRQGEHFCGGSLVKENWVISTRQCFSS 548

  Fly   182 MGRNLTA--AILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRL 244
            ...:|:.  |::|...::..||           .|....|.|.:|:.....|.|      .:|:|
Frog   549 CDADLSGYQAVMGTLFKNPSPD-----------DPDRQSVPISKIVCGPSDSSL------VMLKL 596

  Fly   245 SRPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSGSSKIKQKAMLHIQPQDQCQE 309
            .|||.......|  :||||:  ||....| :..:::|||.|..:|...:.:.|:.||...|:|.:
Frog   597 ERPVTLNSRVAL--ICLPPE--RYIVPEA-TKCEIAGWGDTGGTGHDNVLKIAIFHIISNDECNK 656

  Fly   310 AFYKDTKITLADSQMCAGG-EIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTAL 373
            . |:..:..:.|::||... .:.|.:|.||.||||....:..    :| |.||: :..:.||...
Frog   657 N-YRSQRNKVLDNEMCTKPVPVDVGACEGDYGGPLACLTHDC----WV-LEGVI-VPARGCGKKN 714

  Fly   374 FSGIYTRVSSYMDWIESTIR 393
            ...|:||||.|:|||...::
Frog   715 QPAIFTRVSVYVDWINKVMK 734

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	73/261 (28%)
		Tryp_SPc	133..391	CDD:238113	74/262 (28%)
mst1	XP_004915630.2	PAN_AP_HGF	36..114	CDD:238532
		KR	118..198	CDD:214527
		KR	201..279	CDD:214527
		KR	308..390	CDD:214527
		KR	397..474	CDD:412161
		Tryp_SPc	506..732	CDD:238113	74/263 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910