DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and f12

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_017947702.2	Gene:	f12 / 100493769	XenbaseID:	XB-GENE-1004811	Length:	597	Species:	Xenopus tropicalis

Alignment Length:	357	Identity:	105/357 - (29%)
Similarity:	155/357 - (43%)	Gaps:	64/357 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 CF--SRQRPDLVCC--PRETNIIPPLAPRISNGTTNATSSTTTLKLLP---RTTPRPPSGIDQLP 119
            ||  ..||.....|  ||.|.:....||.....|.:.|.|:......|   ..|..|..|...||
Frog   278 CFVMKEQRLSWEHCLIPRCTQLAGTTAPPKVTKTPSPTKSSNHSASTPSPSNDTQGPVDGRIDLP 342

  Fly   120 EHPYCGSAFSF------RLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHC 178
            ..  ||..|..      |:|||........|:...|..:      ::.||.|.|:..|::|||||
Frog   343 VD--CGRKFQKTPSIMPRIVGGLVALPASHPYIAALYID------NHFCGGSLISPCWIVTAAHC 399

  Fly   179 IHTMGRNLT--AAILGEWNRDTDPDCENDLNGVRECAPPH-IRVTIDRILPHAQYSELNYRNDIA 240
            : ....|:|  :.:||:...:|              ...| :.:.:::.:.|.:|.....::|||
Frog   400 L-DQRPNVTKISVVLGQSRFNT--------------TDQHTVTLLVEKYILHEKYYGDTLQHDIA 449

  Fly   241 LLRLSRPVNWL----QMQNLEPVCLPPQRGRYANQLAGSAAD--VSGWGKTESSGSSK---IKQK 296
            |::: :.:|.|    ..|.::|:|||.|     .::|.|...  |:|||. :..|:..   ..|:
Frog   450 LVKV-KSINGLCASEFSQFVQPICLPQQ-----FKMAESTKQCVVAGWGH-QYEGAEHYAFFLQE 507

  Fly   297 AMLHIQPQDQCQEAFYKDTKITLADSQMCAG-GEIGVDSCSGDSGGPLTVEANTASGNRYVYLAG 360
            |.:.|.|..|||.......:  :....:||| .|.|||:|.|||||||..|.:..     :.|.|
Frog   508 ASMPIIPYTQCQSPSVHGDR--MLPGMLCAGFMEGGVDACQGDSGGPLVCEVDGR-----IELHG 565

  Fly   361 VVSIGRKHCGTALFSGIYTRVSSYMDWIESTI 392
            |||.| ..|......|:||.|:||.|||.:.|
Frog   566 VVSWG-SGCAEENKPGVYTAVTSYTDWIRANI 596

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829	5/15 (33%)
		Tryp_SPc	131..388	CDD:214473	80/269 (30%)
		Tryp_SPc	133..391	CDD:238113	81/270 (30%)
f12	XP_017947702.2	fn2	46..87	CDD:394995
		EGF_CA	95..129	CDD:238011
		KR	213..298	CDD:214527	7/19 (37%)
		Tryp_SPc	359..595	CDD:238113	81/271 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910