DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and tmprss15

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_031752048.1	Gene:	tmprss15 / 100490249	XenbaseID:	XB-GENE-999987	Length:	994	Species:	Xenopus tropicalis

Alignment Length:	412	Identity:	115/412 - (27%)
Similarity:	173/412 - (41%)	Gaps:	86/412 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 CNSVEF--GRGTCI-------EKKDCDFYAVDKLMELASKQQC---FSRQRPDLV---------- 71
            |||..|  |.|.||       :.:|||        :...::.|   |:.....||
Frog   620 CNSTSFQCGSGECIPNTAVCDKHRDCD--------DGTDERHCVRLFNSSMSGLVQFKVQSEWHT 676

  Fly    72 CCPRETN--IIPPLAPRISNGTTNATSSTT----------------TLKLLPRTTPRPPSGIDQL 118
            .|....|  |...:..|:..|..|.||:..                :|.|||.......|.|...
Frog   677 ACIDHWNEDISNDICHRLGLGNVNLTSAVLSEGNGPFVTLIQVEDGSLSLLPSDQCANQSVIHIQ 741

  Fly   119 PEHPYCGSAF-----SFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHC 178
            .:...||...     ..::|||.:..|..:||...|.|     .....||||.:.|.||::||||
Frog   742 CQQRECGKRLVPIKSGSKIVGGSDAALGAWPWIVSLYY-----NDRQTCGASLVNQEWLVSAAHC 801

  Fly   179 IHTMGRNLTAAILGEWNRDTDPDCENDLNGVRECAPPHIRV-TIDRILPHAQYSELNYRNDIALL 242
            ::  ||||   |...|....  ....:||    ...|.|.. .||:|:.:.||:.....:||.::
Frog   802 VY--GRNL---IPSNWKARL--GLHTNLN----LTQPQIATQMIDQIVINPQYNRRTKDSDIVMM 855

  Fly   243 RLSRPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSGS-SKIKQKAMLHIQPQDQ 306
            .|...||:  ...::|:|||.....::   .|....::|||:|:|.|. ..|.|:|.:.:....:
Frog   856 HLQFKVNY--SDYIQPICLPETDQEFS---VGINCSIAGWGRTQSGGPVPNILQEAEIPLISNHK 915

  Fly   307 CQEAFYKDTKITLADSQMCAG-GEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCG 370
            ||:..   .:..:.|:.:|.| .|.|:|:|.||||||:..:.|    |.: :|.||.|.| ..|.
Frog   916 CQQQM---PEYNITDNMVCGGYEEGGIDTCQGDSGGPMMCQQN----NEW-FLVGVTSFG-YGCA 971

  Fly   371 TALFSGIYTRVSSYMDWIESTI 392
            .....|:|.||:.:.:||:|.|
Frog   972 QPSRPGVYVRVTEFTNWIKSFI 993

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829	15/66 (23%)
		Tryp_SPc	131..388	CDD:214473	80/259 (31%)
		Tryp_SPc	133..391	CDD:238113	82/260 (32%)
tmprss15	XP_031752048.1	SEA	36..>103	CDD:396113
		LDLa	157..190	CDD:197566
		CUB	199..305	CDD:238001
		MAM	321..478	CDD:395504
		CUB	501..608	CDD:395345
		LDLa	620..654	CDD:238060	11/41 (27%)
		SR	655..746	CDD:214555	17/90 (19%)
		Tryp_SPc	760..991	CDD:238113	82/260 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910