DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and hgfac

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_002939269.3	Gene:	hgfac / 100485696	XenbaseID:	XB-GENE-940012	Length:	595	Species:	Xenopus tropicalis

Alignment Length:	298	Identity:	87/298 - (29%)
Similarity:	142/298 - (47%)	Gaps:	63/298 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   118 LPEHPYCGSAFSFRLV------GGHNTGLFEFPWTTLLEYETVSG---GKDYACGASFIAQRWLL 173
            :|..|.||.....|:|      ||::......||        |:|   | :|.|..|.|...|::
Frog   332 VPAPPKCGKKHEKRVVARGRILGGNSALPGSHPW--------VAGIYIG-NYFCAGSLIQPCWVV 387

  Fly   174 TAAHCI-HTMGRNLTAAILGE--WNRDTDPDCENDLNGVRECAPPHIRVT----IDRILPHAQYS 231
            :||||. .:..::....:||:  :|:.||                   ||    ::|.:.:.:||
Frog   388 SAAHCFADSPSKSKIRVVLGQHFFNQTTD-------------------VTQTFEVERYIFYDKYS 433

  Fly   232 ELNYRN--DIALLRLSRPVNWL--QMQNLEPVCLPPQRGRYANQLAGSAADVSGWGK--TESSGS 290
            ... ||  ||.|::|.|..|..  :.|.::.:|||.....:|:.   ....::|||:  .:|:..
Frog   434 VFK-RNEHDIVLIKLKRINNACAKKTQFVQTICLPDVSAPFADD---HHCQIAGWGRMHEDSTEY 494

  Fly   291 SKIKQKAMLHIQPQDQCQEAFYKDTKITLADSQMCAG-GEIGVDSCSGDSGGPLTVEANTASGNR 354
            ::..|:|::.:.|.::|........:|  :::..||| .:..:|||.|||||||..|.:..|
Frog   495 AQNLQEAIVPLVPDNKCSSPEIYGAEI--SENMFCAGYFDCTIDSCQGDSGGPLACEKDKIS--- 554

  Fly   355 YVYLAGVVSIGRKHCGTALFSGIYTRVSSYMDWIESTI 392
              ||.|:||.| :.||.....|:||:||:|:|||...|
Frog   555 --YLWGIVSWG-EGCGNHNKPGVYTKVSNYVDWINRKI 589

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	80/279 (29%)
		Tryp_SPc	133..391	CDD:238113	81/280 (29%)
hgfac	XP_002939269.3	FN2	52..98	CDD:238019
		EGF_CA	109..145	CDD:238011
		FN1	147..185	CDD:238018
		KR	235..319	CDD:294073
		Tryp_SPc	351..585	CDD:214473	78/273 (29%)
		Tryp_SPc	352..588	CDD:238113	80/275 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910