DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and tmprss15

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_001919639.2	Gene:	tmprss15 / 100148042	ZFINID:	ZDB-GENE-091204-83	Length:	990	Species:	Danio rerio

Alignment Length:	347	Identity:	98/347 - (28%)
Similarity:	152/347 - (43%)	Gaps:	73/347 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    54 MELASKQQCFSRQRPDLVCCPRETNIIPPLAPRISNGTTNATSSTTTLKLLPRTTPRPPSGIDQL 118
            :||....:|.|.:...|.|               :|.........:..|::..|..:...
Zfish   702 LELKPSDKCISEKIVSLHC---------------NNQPCGVRKVPSKSKIIEETDGKKEG----- 746

  Fly   119 PEHPYCGSAFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMG 183
                        |:|||.:.....:||...|::   .||  :||||:.|.:.||:|||||::  |
Zfish   747 ------------RVVGGQDAQRGAWPWMVSLQW---LGG--HACGATLIDREWLITAAHCVY--G 792

  Fly   184 RNLT----AAILGEWNRDTDPDCENDLNGVRECAPPHIRV-TIDRILPHAQYSELNYRNDIALLR 243
            ||:.    ||:||             |:...|...|:.:| ::|:::.|..|::....:|.||:.
Zfish   793 RNVQLSNWAAVLG-------------LHAQFETINPNKQVFSVDQVIMHKHYNKRTKESDFALMH 844

  Fly   244 LSRPVNWLQMQNLEPVCLPPQRGRYANQLAGSAADVSGWGKTESSG-SSKIKQKAMLHIQPQDQC 307
            |..||::...  ::|:|||.....:..   |....::|||....|| .:.:.|:|::.:....||
Zfish   845 LKTPVSYTDY--VQPICLPDPGAHFEE---GRKCFIAGWGLLSESGLKADVLQQAVVPLLSNTQC 904

  Fly   308 QEAFYKDTKITLADSQMCAG-GEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGT 371
            ||..   .:....:..|||| .|.|||:|.|||||||..|..    ..:| |.|..|.| ..||.
Zfish   905 QEWL---PEYNFTERMMCAGYAEGGVDTCQGDSGGPLMCEEE----GHWV-LVGATSFG-IGCGR 960

  Fly   372 ALFSGIYTRVSSYMDWIESTIR 393
            ....|.|.|||.::||:....|
Zfish   961 PQRPGAYARVSQFVDWVAENRR 982

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829	6/19 (32%)
		Tryp_SPc	131..388	CDD:214473	87/263 (33%)
		Tryp_SPc	133..391	CDD:238113	87/264 (33%)
tmprss15	XP_001919639.2	SEA	19..>89	CDD:279699
		LDLa	142..175	CDD:238060
		CUB	183..288	CDD:238001
		MAM	302..457	CDD:279023
		MAM	302..457	CDD:99706
		CUB	477..586	CDD:238001
		LDLa	596..630	CDD:238060
		SRCR_2	653..728	CDD:295335	7/40 (18%)
		Tryp_SPc	747..977	CDD:214473	87/263 (33%)
		Tryp_SPc	748..980	CDD:238113	87/265 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910