DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and proc.2

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	NP_001120289.1	Gene:	proc.2 / 100145345	XenbaseID:	XB-GENE-5882297	Length:	681	Species:	Xenopus tropicalis

Alignment Length:	372	Identity:	105/372 - (28%)
Similarity:	149/372 - (40%)	Gaps:	77/372 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 GNCNSVEFGRG--TCIEKKDCDFYAVDKLMELASKQQCFSRQRPDLVCCPRETNIIPPLAPRISN 89
            |..||.|:|:|  ...|||..:..::|.                         |.|.........
Frog   367 GGMNSTEWGQGDDPTAEKKPINKTSLDH-------------------------NEIGASVRAART 406

  Fly    90 GTTNATSSTTTLKLLPRTTPRPPSGIDQLPEHPYCGSAFSFRLVGGHNTGLFEFPWTTLLEYETV 154
            ||:.:.....             .|:..:....|.......|:|||....|.:.||..|:.....
Frog   407 GTSKSVWEEN-------------HGLASVEPDDYNTPDGDVRIVGGMRCELGQCPWQVLIRNNRG 458

  Fly   155 SGGKDYACGASFIAQRWLLTAAHCIHT-MGRNLTAAILGEWNRDTDPDCENDLNGVRECAPPHIR 218
            .|    .||.|.|:.||:|:||||..: :..::|......:.||.|..                :
Frog   459 FG----FCGGSLISSRWVLSAAHCFESQIPHHVTIGDYDTYRRDMDEQ----------------K 503

  Fly   219 VTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQNLEPVCLP-PQRGRYANQLAGSAADVSGW 282
            :.:.::..|..|....|.:|||||.|..|..:.:..  .|:||| |..|:...| .|....||||
Frog   504 IAVLQVFSHPNYLAEFYDHDIALLFLRSPAMFGEYS--RPICLPNPGLGKMLTQ-EGQTGQVSGW 565

  Fly   283 GKTESSGS-SKIKQKAMLHIQPQDQCQEAFYKDTKITLADSQMCAGGEIGV-DSCSGDSGGPLTV 345
            |.|...|. ::...|..|.|..|:.|..:    |:..|..:..|||.:.|| |:||||||||..|
Frog   566 GATRQFGPYTRFLLKVRLPIVSQETCMAS----TENILTGNMFCAGYKEGVKDACSGDSGGPFAV 626

  Fly   346 EANTASGNRYVYLAGVVSIGRKHCGTALFSGIYTRVSSYMDWIESTI 392
            ..:..     .:|.||||.| ..|......|:||||::||.||:.||
Frog   627 LFHDT-----WFLVGVVSWG-DGCAEKGKYGVYTRVANYMPWIKETI 667

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829	9/46 (20%)
		Tryp_SPc	131..388	CDD:214473	85/260 (33%)
		Tryp_SPc	133..391	CDD:238113	86/261 (33%)
proc.2	NP_001120289.1	GLA	19..80	CDD:214503
		EGF_CA	81..117	CDD:238011
		FXa_inhibition	123..160	CDD:373209
		Tryp_SPc	436..666	CDD:238113	86/262 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920