DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and gzma

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_012808240.1	Gene:	gzma / 100135014	XenbaseID:	XB-GENE-482759	Length:	267	Species:	Xenopus tropicalis

Alignment Length:	270	Identity:	72/270 - (26%)
Similarity:	120/270 - (44%)	Gaps:	58/270 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   132 LVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTAAILGEWNR 196
            ::.|........|:...:...|.|      ||.:.|.|.|:||||||:    .|.:..|||
Frog    35 IIDGREAASHSRPYMAYIYSRTGS------CGGTLIKQNWVLTAAHCV----VNNSEVILG---- 85

  Fly   197 DTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALL------RLSRPVNWLQMQN 255
                     .:.|:.......|.::.|.:||..:......:||.||      :|::.|:.|::..
Frog    86 ---------AHKVKSRENEQQRFSVARAIPHPCFEWKKKIHDIQLLQIKGAAKLNKFVSVLKLPT 141

  Fly   256 LEPVCLPPQRGRYANQLAGSAADVSGWGKTESSGS--SKIKQKAMLHIQPQDQCQEAFYKDTKIT 318
            .:....|           ||:...:|||.|:.:|.  |.:.::..:.:..:..|.: .||..|..
Frog   142 TDMDVKP-----------GSSCSTAGWGVTKPNGKTPSDVLREVNVTVVDRGTCNK-IYKKFKTE 194

  Fly   319 LADSQMCAG----GEIGVDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSGIYT 379
            ::.:.:|||    .:...|:|.|||||||      ..|..:   :|:||.|:| ||...:.||||
Frog   195 ISTNMLCAGAPKKSDKKYDACQGDSGGPL------ICGKEF---SGIVSFGKK-CGDPKYPGIYT 249

  Fly   380 RVSS-YMDWI 388
            |::: |:.||
Frog   250 RLTARYLQWI 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	70/268 (26%)
		Tryp_SPc	133..391	CDD:238113	72/269 (27%)
gzma	XP_012808240.1	Tryp_SPc	35..262	CDD:238113	72/270 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910