DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ser7 and LOC100004411

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_001343728.4	Gene:	LOC100004411 / 100004411	-ID:	-	Length:	494	Species:	Danio rerio

Alignment Length:	322	Identity:	100/322 - (31%)
Similarity:	152/322 - (47%)	Gaps:	53/322 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    88 SNGTTNATSSTTTL----KLLPRTTPRPPSGI---DQLPEHPYCGSAFS-----FRLVGGHNTGL 140
            :|.|.::||.:..|    ..|..:|.:..:.:   |||.:   .||.|:     .|:|||.....
Zfish   196 ANHTHSSTSPSHPLHHNRSALENSTHQNQTELTAPDQLLD---TGSDFTGGNEDTRIVGGQLQRQ 257

  Fly   141 FEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMGRNLTAAILGEWNRDTDPDCEND 205
            ...||..||..|...|    .||.|.|.|||::|||||:.....::|   :|:::: ..||.:..
Zfish   258 GGSPWQVLLRREDEYG----FCGGSLINQRWVITAAHCLQQTPHHIT---IGDYDK-MRPDKDEQ 314

  Fly   206 LNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLRLSRPVNWLQMQNLEPVCLPPQRGRYAN 270
                        ::|:::|:||..|.|..:.:|||||.||..|......:  |.|||.  ...|.
Zfish   315 ------------KITVEKIIPHPHYHEYTFDSDIALLYLSSAVTLGPFAS--PACLPD--ANLAE 363

  Fly   271 QL--AGSAADVSGWGKTE-SSGSSKIKQKAMLHIQPQDQCQEAFYKDTKITLADSQMCAGGEI-G 331
            :|  .|....|||||.|. ...||:..:|..|.:..|..|    ...|:..:.|:..|||..: .
Zfish   364 RLMKPGEQGLVSGWGSTHYLQRSSRFLRKVQLPVVEQKSC----INSTEQIITDNMFCAGFLMEE 424

  Fly   332 VDSCSGDSGGPLTVEANTASGNRYVYLAGVVSIGRKHCGTALFSGIYTRVSSYMDWIESTIR 393
            :|:|:||||||..|.....     .:|.||||.|.: |.:....|:|||:.:|:.||:..::
Zfish   425 MDACTGDSGGPFIVNYRGT-----WFLTGVVSWGER-CASQGKYGVYTRLGNYLSWIQEEMK 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	85/260 (33%)
		Tryp_SPc	133..391	CDD:238113	86/261 (33%)
LOC100004411	XP_001343728.4	GLA	22..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	128..164	CDD:291342
		Tryp_SPc	248..475	CDD:214473	85/260 (33%)
		Tryp_SPc	249..477	CDD:238113	86/261 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920