DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ser7 and tmprss3a

DIOPT Version :9

Sequence 1:	NP_572582.1	Gene:	Ser7 / 31917	FlyBaseID:	FBgn0019929	Length:	397	Species:	Drosophila melanogaster
Sequence 2:	XP_021334565.1	Gene:	tmprss3a / 100000148	ZFINID:	ZDB-GENE-070912-70	Length:	543	Species:	Danio rerio

Alignment Length:	289	Identity:	89/289 - (30%)
Similarity:	136/289 - (47%)	Gaps:	58/289 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   124 CGS--AFSFRLVGGHNTGLFEFPWTTLLEYETVSGGKDYACGASFIAQRWLLTAAHCIHTMG--- 183
            |||  .||.|:|||:.:...:|||...|.::     .::.||.|.|..||:||||||::.:.
Zfish   288 CGSRPKFSARIVGGNLSAEGQFPWQVSLHFQ-----NEHLCGGSIITSRWILTAAHCVYGIAYPM 347

  Fly   184 -----RNLTAAILGEWNRDTDPDCENDLNGVRECAPPHIRVTIDRILPHAQYSELNYRNDIALLR 243
                 ..||               |..||.|:..|       :::|:.|::|......:||||::
Zfish   348 YWMVYAGLT---------------ELPLNAVKAFA-------VEKIIYHSRYRPKGLDHDIALMK 390

  Fly   244 LSRPVNWLQMQNLEPVCLPPQRGRYANQLA-GSAADVSGWGKTESSGSSKIKQK-AMLHIQPQDQ 306
            |::|:.:..|  :||:|||    .:..|.. |....:||||.||..|.:.:.|. |.:.:.....
Zfish   391 LAQPLTFNGM--VEPICLP----NFGEQFEDGKMCWISGWGATEDGGDASVSQHCASVPLISNKA 449

  Fly   307 C-QEAFYKDTKITLADSQMCAGG-EIGVDSCSGDSGGPLTVEANTASGNRYVY-LAGVVSIGRKH 368
            | |...|:.   .|....:|||. :.|.|||.|||||||..|.::      :: |.|..|.| :.
Zfish   450 CSQPEVYQG---YLTAGMICAGYLDGGTDSCQGDSGGPLACEDSS------IWKLVGATSWG-QG 504

  Fly   369 CGTALFSGIYTRVSSYMDWIESTIRANRI 397
            |......|:|||::..:.||...:....|
Zfish   505 CAEKNKPGVYTRITQSLTWIHLQMEREEI 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ser7	NP_572582.1	CLIP	29..74	CDD:197829
		Tryp_SPc	131..388	CDD:214473	81/269 (30%)
		Tryp_SPc	133..391	CDD:238113	82/270 (30%)
tmprss3a	XP_021334565.1	LDLa	154..186	CDD:238060
		SRCR_2	191..292	CDD:317845	3/3 (100%)
		Tryp_SPc	298..525	CDD:238113	81/269 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910