Protein Alignment CARPB and CA12

DIOPT Version :10

• Sequence 1: NP_572581.1
• Gene: CARPB / 31915
• FlyBaseID: FBgn0052698
• Length: 327
• Species: Drosophila melanogaster
• Sequence 2: NP_001209.1
• Gene: CA12 / 771
• HGNCID: 1371
• Length: 354
• Species: Homo sapiens
• Alignment Length: 301
• Identity: 99/301 - (32%)
• Similarity: 150/301 - (49%)
• Gaps: 26/301 - (8%)

  Fly     4 LQALCCTLLLLLARMQVLLAVSWEDWWTYDGISGPAFWGLINPEWSLCNKGRRQSPVNLEPQRLL 68
            |.|....||::|.......|......|||.|..|...|   :.::..|. |..|||::|....|.
Human     6 LHAAAVLLLVILKEQPSSPAPVNGSKWTYFGPDGENSW---SKKYPSCG-GLLQSPIDLHSDILQ 66

  Fly    69 FDPNLRPMHIDKHRISG----LITNTGHSVIFTAGNDTVANYDGMQTPVNISGGPLSYRYRFHEI 129
            :|.:|.|:....:.:|.    |:||.||||.....:|           ::|.|  |..||...::
Human    67 YDASLTPLEFQGYNLSANKQFLLTNNGHSVKLNLPSD-----------MHIQG--LQSRYSATQL 118

  Fly   130 HMHYG-LNDQFGSEHSVEGYTFPAEIQIFGYNSQLYANFSDALNRAQGIVGVSILLQLGDLSNAE 193
            |:|:| .||..||||:|.|..|.||:.|..|||.||.:.|.|.|:::|:..:::|:::|.. |..
Human   119 HLHWGNPNDPHGSEHTVSGQHFAAELHIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSF-NPS 182

  Fly   194 LRMLTDQLERIRYGGDEAFVKRLSIRGLLPD-TDHYMTYDGSTTAPACHETVTWVVLNKPIYITK 257
            ...:...|:.::|.|.||||...:|..|||: |..|..|.||.|.|.|:.||.|.|...|:.|::
Human   183 YDKIFSHLQHVKYKGQEAFVPGFNIEELLPERTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQ 247

  Fly   258 QQLHALRRLMQGSPDHPKAP--LGNNYRPPQPLLHRPIRTN 296
            :||.||...:..:.....:|  :.||:|..|....|.:.|:
Human   248 EQLLALETALYCTHMDDPSPREMINNFRQVQKFDERLVYTS 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CARPB	NP_572581.1	alpha_CARP_X_XI_like	37..298	CDD:239395	89/268 (33%)
CA12	NP_001209.1	alpha_CA_XII_XIV	39..289	CDD:239400	89/268 (33%)