Protein Alignment CARPB and CA7

DIOPT Version :10

• Sequence 1: NP_572581.1
• Gene: CARPB / 31915
• FlyBaseID: FBgn0052698
• Length: 327
• Species: Drosophila melanogaster
• Sequence 2: NP_005173.1
• Gene: CA7 / 766
• HGNCID: 1381
• Length: 264
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 93/270 - (34%)
• Similarity: 147/270 - (54%)
• Gaps: 18/270 - (6%)

  Fly    30 WTYDGISGPAFWGLINPEWSLCNKGRRQSPVNLEPQRLLFDPNLRPMHIDKHRISGL-ITNTGHS 93
            |.|....||:.|..:.|    ..:|.||||:|:...:.::.|:|:|:.:.......| |||.|||
Human     7 WGYGQDDGPSHWHKLYP----IAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNGHS 67

  Fly    94 --VIFTAGNDTVANYDGMQTPVNISGGPLSYRYRFHEIHMHYGLNDQFGSEHSVEGYTFPAEIQI 156
              |.|...:|...          ::||||...||..:.|.|:|.....||||:|:|.:||:|:.:
Human    68 VQVDFNDSDDRTV----------VTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHL 122

  Fly   157 FGYNSQLYANFSDALNRAQGIVGVSILLQLGDLSNAELRMLTDQLERIRYGGDEAFVKRLSIRGL 221
            ..:|::.|:.|.:|.:...|:..|.:.|:.|| .:..:..|||.|..:|:.|.:|.....:.:.|
Human   123 VHWNAKKYSTFGEAASAPDGLAVVGVFLETGD-EHPSMNRLTDALYMVRFKGTKAQFSCFNPKCL 186

  Fly   222 LPDTDHYMTYDGSTTAPACHETVTWVVLNKPIYITKQQLHALRRLMQGSPDHPKAPLGNNYRPPQ 286
            ||.:.||.||.||.|.|...|:|||:||.:||.|:::|:...|.|:..|.|..:..:.||:||||
Human   187 LPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNNFRPPQ 251

  Fly   287 PLLHRPIRTN 296
            ||..|.::.:
Human   252 PLKGRVVKAS 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CARPB	NP_572581.1	alpha_CARP_X_XI_like	37..298	CDD:239395	91/263 (35%)
CA7	NP_005173.1	alpha_CA_VII	27..262	CDD:239402	87/246 (35%)