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Protein Alignment CARPB and CA3

DIOPT Version :9

Sequence 1:	NP_001245593.1	Gene:	CARPB / 31915	FlyBaseID:	FBgn0052698	Length:	327	Species:	Drosophila melanogaster
Sequence 2:	NP_005172.1	Gene:	CA3 / 761	HGNCID:	1374	Length:	260	Species:	Homo sapiens

Alignment Length:	274	Identity:	94/274 - (34%)
Similarity:	144/274 - (52%)	Gaps:	21/274 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 WTYDGISGPAFWGLINPEWSLCNKGRRQSPVNLEPQRLLFDPNLRPMHIDKHRISG-LITNTGHS 93
            |.|...:||..|..:.|.    .||..||||.|..:.:..||:|:|..:.....|. .|.|.|.:
Human     5 WGYASHNGPDHWHELFPN----AKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTILNNGKT 65

  Fly    94 --VIFTAGNDTVANYDGMQTPVNISGGPLSYRYRFHEIHMHYGLNDQFGSEHSVEGYTFPAEIQI 156
              |:|   :||   ||...    :.||||...||..:.|:|:|.:|..||||:|:|..:.||:.:
Human    66 CRVVF---DDT---YDRSM----LRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHL 120

  Fly   157 FGYNSQLYANFSDALNRAQGIVGVSILLQLGDLSNAELRMLTDQLERIRYGGDEAFVKRLSIRGL 221
            ..:|.: |..|.:||.:..||..:.|.|::|. .|.|.::..|.|::|:..|.||...:.....|
Human   121 VHWNPK-YNTFKEALKQRDGIAVIGIFLKIGH-ENGEFQIFLDALDKIKTKGKEAPFTKFDPSCL 183

  Fly   222 LPDTDHYMTYDGSTTAPACHETVTWVVLNKPIYITKQQLHALRRLMQGSPDHPKAPLGNNYRPPQ 286
            .|....|.||.||.|.|.|.|.:.|::|.:|:.::..|:..||.|:..:.:.|..||.:|:||||
Human   184 FPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPLVSNWRPPQ 248

  Fly   287 PLLHRPIRTNIDFK 300
            |:.:|.:|.:  ||
Human   249 PINNRVVRAS--FK 260

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.