DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CARPB and ca10b

DIOPT Version :9

Sequence 1:	NP_001245593.1	Gene:	CARPB / 31915	FlyBaseID:	FBgn0052698	Length:	327	Species:	Drosophila melanogaster
Sequence 2:	XP_005164153.1	Gene:	ca10b / 568543	ZFINID:	ZDB-GENE-080815-2	Length:	326	Species:	Danio rerio

Alignment Length:	310	Identity:	128/310 - (41%)
Similarity:	178/310 - (57%)	Gaps:	27/310 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 EDWWTY-DGISG-----PAFWGLINPEWSLCNKGRRQSPVNLEPQRLLFDPNLRPMHID--KHRI 83
            :.||.| |.:.|     |:||||:|..|:||..|:||||||:|..|::|||.|.|:.::  :.::
Zfish    29 DGWWAYKDVVQGSFIPVPSFWGLVNTAWNLCAIGKRQSPVNIETSRMIFDPFLNPLRLNAGQRKV 93

  Fly    84 SGLITNTGHSVIFTAGNDTVANYDGMQTPVNISGGPLSYRYRFHEIHMHYGLNDQFGSEHSVEGY 148
            ||.:.|||..|........:         ||||||||||.||..||.:|:|..|..||||.:.|.
Zfish    94 SGTMYNTGRHVSLRPDKSHL---------VNISGGPLSYSYRLEEIRLHFGSEDNRGSEHLLNGQ 149

  Fly   149 TFPAEIQIFGYNSQLYANFSDALNRAQGIVGVSILLQLGDLSNAEL-RMLT-DQLERIRYGGDEA 211
            .||.|:|:..||..||.|:|||:....||..|||.:::.:.:|..| |||. :.:.||.|..|..
Zfish   150 AFPGEVQLIHYNQDLYLNYSDAVRSPNGIAVVSIFMKISEPTNVFLNRMLNRETVTRITYKHDAY 214

  Fly   212 FVKRLSIRGLLPDTDHYMTYDGSTTAPACHETVTWVVLNKPIYITKQQLHALRRLMQGSPDHPKA 276
            .:..|:|..|.|:|..::||:||.|.|.|.||.||:::||||||::.::.:||.|.|..|.....
Zfish   215 LLMGLNIEELYPETSRFITYEGSITIPPCLETATWILMNKPIYISQIEMQSLRLLSQNQPSQIFL 279

  Fly   277 PLGNNYRPPQPLLHRPIRTNIDFKTTKSNGKAACPT--MYREVYYKATSW 324
            .:|:|.||.|.|..|.|||||:|...:.     ||.  |.|. .|:...|
Zfish   280 SMGDNMRPTQTLHQRCIRTNINFSQRRD-----CPNNRMLRP-QYRVNEW 323

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CARPB	NP_001245593.1	alpha_CARP_X_XI_like	37..298	CDD:239395	116/269 (43%)
ca10b	XP_005164153.1	PLN02179	7..257	CDD:177835	101/236 (43%)
ca10b	XP_005164153.1	alpha_CARP_X_XI_like	45..301	CDD:239395	115/264 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579204
Domainoid	1	1.000	233	1.000	Domainoid score	I2331
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	248	1.000	Inparanoid score	I3235
OMA	1	1.010	-	-		QHG45680
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	1	1.000	-	-		FOG0002299
OrthoInspector	1	1.000	-	-		mtm6345
orthoMCL	1	0.900	-	-		OOG6_106561
Panther	1	1.100	-	-	O	PTHR18952
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1354
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.810