DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CARPB and Ca13

DIOPT Version :9

Sequence 1:	NP_001245593.1	Gene:	CARPB / 31915	FlyBaseID:	FBgn0052698	Length:	327	Species:	Drosophila melanogaster
Sequence 2:	NP_001128465.1	Gene:	Ca13 / 499566	RGDID:	1560453	Length:	262	Species:	Rattus norvegicus

Alignment Length:	268	Identity:	93/268 - (34%)
Similarity:	146/268 - (54%)	Gaps:	14/268 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 WTYDGISGPAFWGLINPEWSLCNKGRRQSPVNLEPQRLLFDPNLRPMHIDKHRISG-LITNTGHS 93
            |.||..:||..|..:.|    ...|.:|||:.::.:.:.:|.:|||:.|.....|. :|:|:|||
  Rat     6 WGYDEHNGPIHWNELFP----IADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPASAKIISNSGHS 66

  Fly    94 VIFTAGNDTVANYDGMQTPVNISGGPLSYRYRFHEIHMHYGLNDQFGSEHSVEGYTFPAEIQIFG 158
              |.      .::|..:....:.||||:..||..:.|:|:|..|..||||.|:|..:.||:.:..
  Rat    67 --FN------VDFDDTEDKSVLRGGPLTGSYRLRQFHLHWGSADDHGSEHVVDGVRYAAELHVVH 123

  Fly   159 YNSQLYANFSDALNRAQGIVGVSILLQLGDLSNAELRMLTDQLERIRYGGDEAFVKRLSIRGLLP 223
            :||..|.:|.:|.:.:.|:..:.:.||:|: .|.:|:.:||.|:.|:..|.:..........|||
  Rat   124 WNSDKYPSFVEAAHESDGLAVLGVFLQIGE-HNPQLQKITDILDSIKEKGKQTRFTNFDPLCLLP 187

  Fly   224 DTDHYMTYDGSTTAPACHETVTWVVLNKPIYITKQQLHALRRLMQGSPDHPKAPLGNNYRPPQPL 288
            .:..|.||.||.|.|...|:|||:||.:||.|:.|||...|.|:..:.....|.|.:|:||||||
  Rat   188 SSWDYWTYPGSLTVPPLLESVTWIVLKQPISISSQQLARFRSLLCTAEGESAAFLLSNHRPPQPL 252

  Fly   289 LHRPIRTN 296
            ..|.:|.:
  Rat   253 KGRRVRAS 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CARPB	NP_001245593.1	alpha_CARP_X_XI_like	37..298	CDD:239395	90/261 (34%)
Ca13	NP_001128465.1	alpha_CA_I_II_III_XIII	2..261	CDD:239393	93/268 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339463
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.750