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Protein Alignment CARPB and CA5B

DIOPT Version :9

Sequence 1:	NP_001245593.1	Gene:	CARPB / 31915	FlyBaseID:	FBgn0052698	Length:	327	Species:	Drosophila melanogaster
Sequence 2:	NP_009151.1	Gene:	CA5B / 11238	HGNCID:	1378	Length:	317	Species:	Homo sapiens

Alignment Length:	279	Identity:	87/279 - (31%)
Similarity:	142/279 - (50%)	Gaps:	25/279 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 INPEW---SLCNKGRRQSPVNLEPQRLLFDPNLRPMHIDKHRISGL-ITNTGHSVIFTAGNDTVA 104
            ::|.|   .|...|.||||:|:..:..::||.|:|:.|.....:.| :.|.|:|.:....:.|..
Human    48 LHPLWESVDLVPGGDRQSPINIRWRDSVYDPGLKPLTISYDPATCLHVWNNGYSFLVEFEDSTDK 112

  Fly   105 NYDGMQTPVNISGGPLSYRYRFHEIHMHYGLNDQFGSEHSVEGYTFPAEIQIFGYNSQLYANFSD 169
            :.        |.||||.:.||..:.|.|:|..|.:||||:|:...||||:.:..:|:..:.||.|
Human   113 SV--------IKGGPLEHNYRLKQFHFHWGAIDAWGSEHTVDSKCFPAELHLVHWNAVRFENFED 169

  Fly   170 ALNRAQGIVGVSILLQLGDLSNAELRMLTDQLERIRYGGDEAFVKRLSI--RGLLPDTDHYMTYD 232
            |.....|:..:.:.|:||. .:.||:.|.|.|..|::  .:|.|:..|.  ..|:|....|.||.
Human   170 AALEENGLAVIGVFLKLGK-HHKELQKLVDTLPSIKH--KDALVEFGSFDPSCLMPTCPDYWTYS 231

  Fly   233 GSTTAPACHETVTWVVLNKPIYITKQQLHALRRLMQGSPDHPKAPLGNNYRPPQPLLHRPIRT-- 295
            ||.|.|...|:|||::..:|:.:...||...|.|:..|....:..:.:|:||.|||::|.:|:
Human   232 GSLTTPPLSESVTWIIKKQPVEVDHDQLEQFRTLLFTSEGEKEKRMVDNFRPLQPLMNRTVRSSF 296

  Fly   296 ------NIDFKTTKSNGKA 308
                  |:..|...:..:|
Human   297 RHDYVLNVQAKPKPATSQA 315

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.