DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CARPB and ca6

DIOPT Version :9

Sequence 1:	NP_001245593.1	Gene:	CARPB / 31915	FlyBaseID:	FBgn0052698	Length:	327	Species:	Drosophila melanogaster
Sequence 2:	XP_009295179.1	Gene:	ca6 / 100006448	ZFINID:	ZDB-GENE-030131-7091	Length:	538	Species:	Danio rerio

Alignment Length:	276	Identity:	78/276 - (28%)
Similarity:	136/276 - (49%)	Gaps:	29/276 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 DWWTYDGISGPAFWGLINPEWSLCNKGRRQSPVNLEPQRLLFDPNLRPMHIDKH---RISGLITN 89
            |:|||.|......|.   .::..|. |::|||::::.:::.:.|.::.:.:..:   |.|.|:.|
Zfish    24 DYWTYSGELDQKHWA---EKYHDCG-GQQQSPIDIQRRKVRYSPRMQQLELTGYEDIRGSFLMKN 84

  Fly    90 TGHSVIFTAGNDTVANYDGMQTP--VNISGGPLSYRYRFHEIHMHYGLND--QFGSEHSVEGYTF 150
            .||||             .:|.|  :.|:.| ..::|...::|:|:|..|  ..||||:::|..:
Zfish    85 NGHSV-------------EIQLPSTMKITKG-FPHQYTAVQMHLHWGGWDLEASGSEHTMDGIRY 135

  Fly   151 PAEIQIFGYNSQLYANFSDALNRAQGIVGVSILLQLGDLSNAELRMLTDQLERIRYGGDEAFVKR 215
            .||:.:..|||:.|.:|.:|.|:..|:..::...:.|...|.........|..|:|.|....:..
Zfish   136 MAELHVVHYNSEKYPSFEEAKNKPDGLAVLAFFFEDGHFENTYYSDFISNLANIKYVGQSMSISN 200

  Fly   216 LSIRGLLPDT-DHYMTYDGSTTAPACHETVTWVVLNKPIYITKQQLHALRRLMQGSPDHPKAPLG 279
            |::..:|.:. .|:..|.||.|.|.|.|:|.|.|.:.||.::..|   :|:|.....||....|.
Zfish   201 LNVLSMLSENLSHFYRYKGSLTTPPCFESVMWTVFDTPITLSHNQ---IRKLESTLMDHDNKTLW 262

  Fly   280 NNYRPPQPLLHRPIRT 295
            |:||..|||..|.:.:
Zfish   263 NDYRMAQPLNERVVES 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CARPB	NP_001245593.1	alpha_CARP_X_XI_like	37..298	CDD:239395	73/267 (27%)
ca6	XP_009295179.1	alpha_CA	33..281	CDD:320708	73/267 (27%)
ca6	XP_009295179.1	LamG	332..521	CDD:328935
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170579199
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3338
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1377476at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.750