Protein Alignment Sp1 and KLF11

DIOPT Version :9

• Sequence 1: NP_001259388.1
• Gene: Sp1 / 31913
• FlyBaseID: FBgn0020378
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: NP_003588.1
• Gene: KLF11 / 8462
• HGNCID: 11811
• Length: 512
• Species: Homo sapiens
• Alignment Length: 461
• Identity: 129/461 - (27%)
• Similarity: 170/461 - (36%)
• Gaps: 140/461 - (30%)

  Fly    62 SPPPLADAAVGKGFHPWKKSPNSPAAGSSGSSGGGGGGGGSSAGQHSPCAISAASSSSSSGSSGG 126
            :||...|..     .|..::|.||....|                 ..|..:....||:
Human   107 TPPQSPDLV-----EPSTRTPVSPQVTDS-----------------KACTATDVLQSSA------ 143

  Fly   127 QSSRSLSSSASTMVNITASRPLASS-CAAVGGG---STGSSSSASGSQSSSTASAVAAAYGGDLY 187
            ..:|:||..|..  .:....|:.|| |.|.|..   .||.|.:|.
Human   144 VVARALSGGAER--GLLGLEPVPSSPCRAKGTSVIRHTGESPAAC-------------------- 186

  Fly   188 FPNTSTSN---MDNHHMHQGLLGKVEAGAAAFGGVYSRHPYD--WPFNAVTHKEAASVNSGWWDM 247
            ||...|.:   .|:....:.|||..|.       :...|..|  ...|.|:.:..         :
Human   187 FPTIQTPDCRLSDSREGEEQLLGHFET-------LQDTHLTDSLLSTNLVSCQPC---------L 235

  Fly   248 HSAAGSWLDMGG--AGMHSTMANYASENYSS------------------ALSHSLLGSGQHLLQD 292
            |.:.|..|...|  ||....:...:.:||.:                  .|...:..:||..:..
Human   236 HKSGGLLLTDKGQQAGWPGAVQTCSPKNYENDLPRKTTPLISVSVPAPPVLCQMIPVTGQSSMLP 300

  Fly   293 TYKSMLPGQGVGVGVGVGMGGFSLPHSSPSAAAAAAATAAAAAGGS----------PQGGSPSTP 347
            .:....|...||.             ..|..|.||.|......|.:          |||..| .|
Human   301 AFLKPPPQLSVGT-------------VRPILAQAAPAPQPVFVGPAVPQGAVMLVLPQGALP-PP 351

  Fly   348 SPRSQRRYAGRATCDCPNCQEAERLGPAGVHL-------------RKKNIHSCHIPGCGKVYGKT 399
            :|.:....|...|...|       |.||.|.:             |::| :.|..|||.|.|.|:
Human   352 APCAANVMAAGNTKLLP-------LAPAPVFITSSQNCVPQVDFSRRRN-YVCSFPGCRKTYFKS 408

  Fly   400 SHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLAKHV 464
            ||||||||.||||:||.|:|..|.|:|.|||||.||.|||||||:|.||||::||||||||.||.
Human   409 SHLKAHLRTHTGEKPFNCSWDGCDKKFARSDELSRHRRTHTGEKKFVCPVCDRRFMRSDHLTKHA 473

  Fly   465 KTHNGT 470
            :.|..|
Human   474 RRHMTT 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sp1	NP_001259388.1	C2H2 Zn finger	390..409	CDD:275368	14/18 (78%)
		zf-H2C2_2	401..428	CDD:290200	18/26 (69%)
		C2H2 Zn finger	417..439	CDD:275368	13/21 (62%)
		zf-H2C2_2	431..454	CDD:290200	16/22 (73%)
		zf-C2H2	445..467	CDD:278523	15/21 (71%)
		C2H2 Zn finger	447..467	CDD:275368	14/19 (74%)
KLF11	NP_003588.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	109..128		6/23 (26%)
		COG5048	393..>449	CDD:227381	36/56 (64%)
		zf-C2H2	394..418	CDD:278523	15/23 (65%)
		C2H2 Zn finger	399..418	CDD:275368	14/18 (78%)
		zf-H2C2_2	410..437	CDD:290200	18/26 (69%)
		C2H2 Zn finger	426..448	CDD:275368	13/21 (62%)
		zf-H2C2_2	440..463	CDD:290200	16/22 (73%)
		zf-C2H2	454..476	CDD:278523	15/21 (71%)
		C2H2 Zn finger	456..476	CDD:275368	14/19 (74%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910