Protein Alignment Sp1 and Klf10

DIOPT Version :10

• Sequence 1: NP_001259388.1
• Gene: Sp1 / 31913
• FlyBaseID: FBgn0020378
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: XP_063120372.1
• Gene: Klf10 / 81813
• RGDID: 621652
• Length: 635
• Species: Rattus norvegicus
• Alignment Length: 476
• Identity: 124/476 - (26%)
• Similarity: 191/476 - (40%)
• Gaps: 120/476 - (25%)

  Fly    24 ISNIATHLQKPQVNPDHPSLRGTPLAMLA----------AQCNKLSNKSPP-----PLADAAVGK 73
            ::.::...::..:.|..|.|:..|...|.          :|.:.|:..:||     .|:|||...
  Rat   219 VTPVSDTSEEDSLLPGTPDLQTVPAFCLTPPYSPSDFEPSQGSNLTAPAPPTGHFRSLSDAAKPP 283

  Fly    74 GFHPWKKSPNSPAAG----SSGSSGGGGGGGGSSAGQHSPCAISAASSSSSSGSSGGQSSRSLSS 134
            ...|:|:...||.|.    .:.::........:....|..|.:.|||..:...:         |.
  Rat   284 SIAPFKEEEKSPLAAPPLPKAQATSVIRHTADAQLCNHQSCPVKAASILNYQDN---------SF 339

  Fly   135 SASTMVNITASR---PLASSCAAVGGG--STGSSSSASGSQSSSTASAVAAAYGGDLYFPNT--- 191
            ...|.:|:.|:|   |    ||||...  ....|::|:|::.:.||..       |...|::
  Rat   340 RRRTHINVEATRKNIP----CAAVSPNRPKPEPSTAANGAEKAGTAPY-------DFAVPSSETV 393

  Fly   192 ---STSNMDNHHMHQGLLGKVEAGAAAFGGVYSRHPYDWPFNAVTHKEAASVNSGWWDMHSAAGS 253
               |:.......:.:.:|  :.:...:.|||    |   |...:........|:
  Rat   394 ICRSSQPAPTSPVQKSVL--MSSPTVSTGGV----P---PLPVICQMVPLPANN----------- 438

  Fly   254 WLDMGGAGMHSTMANYASENYSSALSHSLLGSGQHLLQDTYKSMLPGQGVGVGVGVGMGGFSLPH 318
                   .:.:|:...:..:...|:...:|..|..:.:.|...::|...|
  Rat   439 -------SLVTTVVPSSPPSQPPAVCSPVLFMGTQVPKGTVMFVVPQPVV--------------- 481

  Fly   319 SSPSAAAAAAATAAAAAGGSPQGG--SPSTPSPRSQRRYAGRATCDCPNCQEAERLGPAGVHLRK 381
            .||.....           ||.|.  ||..|:|...              ..|.|:.|. :...:
  Rat   482 QSPKPPVV-----------SPNGTRLSPIAPAPGFS--------------PSAARVTPQ-IDSSR 520

  Fly   382 KNIHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFA 446
            ...|.|..|||||.|.|:||||||:|.||||:||.|:|..|.:||.|||||.||.|||||||:||
  Rat   521 VRSHICSHPGCGKTYFKSSHLKAHVRTHTGEKPFSCSWKGCERRFARSDELSRHRRTHTGEKKFA 585

  Fly   447 CPVCNKRFMRSDHLAKHVKTH 467
            ||:|::||||||||.||.:.|
  Rat   586 CPMCDRRFMRSDHLTKHARRH 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sp1	NP_001259388.1	SP6-9-like_N	50..386	CDD:411694	63/367 (17%)
		C2H2 Zn finger	390..409	CDD:275368	14/18 (78%)
		zf-H2C2_2	401..428	CDD:463886	17/26 (65%)
		C2H2 Zn finger	417..439	CDD:275368	13/21 (62%)
		zf-H2C2_2	431..454	CDD:463886	16/22 (73%)
		zf-C2H2	445..467	CDD:395048	15/21 (71%)
		C2H2 Zn finger	447..467	CDD:275368	13/19 (68%)
Klf10	XP_063120372.1	None