Protein Alignment Sp1 and Klf17

DIOPT Version :9

• Sequence 1: NP_001259388.1
• Gene: Sp1 / 31913
• FlyBaseID: FBgn0020378
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: NP_083692.2
• Gene: Klf17 / 75753
• MGIID: 2181068
• Length: 341
• Species: Mus musculus
• Alignment Length: 447
• Identity: 103/447 - (23%)
• Similarity: 146/447 - (32%)
• Gaps: 144/447 - (32%)

  Fly    54 QCNKLSNKSPPPLADAAVGKGFHPWKKSPNSPAAGSSGSSGGGGGGGGSSAGQHSPCA------- 111
            |.||......||:.:..:         .|.|....|||:|           |.|.|.|
Mouse     3 QDNKEQAMHQPPMDNKML---------VPVSNVPVSSGNS-----------GFHQPPATQYLPEM 47

  Fly   112 -----ISAASSSSSSGSSGGQSSRSLSSSASTMVNITASRPLASSC-AAVGGGS----TGSSSS- 165
                 .||.....:......|..|||........:..|..|..:.| .::|.||    .|||.:
Mouse    48 MRSYMASAEELRCNEREWESQLIRSLPEHGVRCPSQLAPIPFQNYCQRSIGRGSHVMPVGSSGTL 112

  Fly   166 ------------ASGSQSSSTASAVAAAYGGDLYFPNTSTSNMDNHHMHQGLLGKVEAGAAAFGG 218
                        ..|..||...|.:|.:....:.:|...|.......:..|:|  :..|.|:.|
Mouse   113 GVTISFSENLMPQGGLPSSRGVSVMAHSSAPAMPYPMPPTVPATTGSLKHGIL--LVPGMASAG- 174

  Fly   219 VYSRHPYDWPFNAVTHKEAASVNSGWWDMHSAAGSWLDMGGAGMHSTMANYASENYSSALSHSLL 283
                          ||               |...::|.                    :.||:.
Mouse   175 --------------TH---------------AVAPFMDQ--------------------MLHSIN 190

  Fly   284 GSGQHLLQDTYKSMLPGQGVGVGVGVGMGGFSLPHSSPSAAAAAAATAAAAAGGSPQGGSPSTPS 348
            .....:|...::.:                  ||..|..:....:.|..     .|....|.||:
Mouse   191 PCNPEMLPARFQQL------------------LPLDSQDSLVTESNTQE-----EPFVREPPTPA 232

  Fly   349 PRSQRRYAGRATCDCPNCQEAERLGPAGVHLRKKNI---HSCHIPGCGKVYGKTSHLKAHLRWHT 410
            |..         .:.|:...       |...|:..:   :.|....|||.|.|.|||.:|.|.||
Mouse   233 PEG---------AESPSTSR-------GATRRQSPVSRPYVCTYNSCGKSYTKRSHLVSHQRKHT 281

  Fly   411 GERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLAKHVKTH 467
            |.:||.|:|..|..:|.|||||.||.|.||..:...|..|::.|||||||.:|.:||
Mouse   282 GVKPFACDWNGCTWKFFRSDELGRHKRIHTRYRPHKCDECDREFMRSDHLRQHKRTH 338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sp1	NP_001259388.1	C2H2 Zn finger	390..409	CDD:275368	10/18 (56%)
		zf-H2C2_2	401..428	CDD:290200	13/26 (50%)
		C2H2 Zn finger	417..439	CDD:275368	12/21 (57%)
		zf-H2C2_2	431..454	CDD:290200	9/22 (41%)
		zf-C2H2	445..467	CDD:278523	10/21 (48%)
		C2H2 Zn finger	447..467	CDD:275368	10/19 (53%)
Klf17	NP_083692.2	COG5048	<22..317	CDD:227381	86/396 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..252		9/58 (16%)
		zf-C2H2	256..280	CDD:278523	11/23 (48%)
		C2H2 Zn finger	261..280	CDD:275368	10/18 (56%)
		C2H2 Zn finger	288..310	CDD:275368	12/21 (57%)
		zf-H2C2_2	302..325	CDD:290200	9/22 (41%)
		zf-C2H2	316..338	CDD:278523	10/21 (48%)
		C2H2 Zn finger	318..338	CDD:275368	10/19 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910