Protein Alignment Sp1 and KLF9

DIOPT Version :10

• Sequence 1: NP_001259388.1
• Gene: Sp1 / 31913
• FlyBaseID: FBgn0020378
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: NP_001197.1
• Gene: KLF9 / 687
• HGNCID: 1123
• Length: 244
• Species: Homo sapiens
• Alignment Length: 155
• Identity: 76/155 - (49%)
• Similarity: 87/155 - (56%)
• Gaps: 24/155 - (15%)

  Fly   320 SPSAAAAAAATAAAAAGGSPQGGSP-------STPSPRSQRRYAGRATCDCPNCQEAERLGPAGV 377
            ||.....:.:.....:|.|| ..||       |.|||.| ..:.|.|.              .|.
Human    88 SPDEDMGSDSDVTTESGSSP-SHSPEERQDPGSAPSPLS-LLHPGVAA--------------KGK 136

  Fly   378 HLRKKNIHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGE 442
            |..:|. |.|...||||||||:||||||.|.|||||||.|.|..|.|:|:|||||.||.||||||
Human   137 HASEKR-HKCPYSGCGKVYGKSSHLKAHYRVHTGERPFPCTWPDCLKKFSRSDELTRHYRTHTGE 200

  Fly   443 KRFACPVCNKRFMRSDHLAKHVKTH 467
            |:|.||:|.|||||||||.||.:.|
Human   201 KQFRCPLCEKRFMRSDHLTKHARRH 225

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sp1	NP_001259388.1	SP6-9-like_N	50..386	CDD:411694	17/72 (24%)
		C2H2 Zn finger	390..409	CDD:275368	15/18 (83%)
		zf-H2C2_2	401..428	CDD:463886	18/26 (69%)
		C2H2 Zn finger	417..439	CDD:275368	13/21 (62%)
		zf-H2C2_2	431..454	CDD:463886	16/22 (73%)
		zf-C2H2	445..467	CDD:395048	15/21 (71%)
		C2H2 Zn finger	447..467	CDD:275368	14/19 (74%)
KLF9	NP_001197.1	KLF9_N	3..144	CDD:409239	17/72 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	80..142		16/69 (23%)
		COG5048	<94..234	CDD:227381	74/149 (50%)
		C2H2 Zn finger	145..167	CDD:275368	16/21 (76%)
		C2H2 Zn finger	175..197	CDD:275368	13/21 (62%)
		C2H2 Zn finger	205..225	CDD:275368	14/19 (74%)