Protein Alignment Sp1 and Klf14

DIOPT Version :10

• Sequence 1: NP_001259388.1
• Gene: Sp1 / 31913
• FlyBaseID: FBgn0020378
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: NP_001128565.1
• Gene: Klf14 / 619665
• MGIID: 3577024
• Length: 325
• Species: Mus musculus
• Alignment Length: 345
• Identity: 103/345 - (29%)
• Similarity: 139/345 - (40%)
• Gaps: 93/345 - (26%)

  Fly   132 LSSSASTMVNITASRPLASSCAA---VGGGSTGSSSSASGSQSSSTASAVAAAYGGDLYFPNTST 193
            :|.|...:::..|:.|..:|.||   ||..|..|:...:||:.......|       |..|..|.
Mouse    17 VSMSTRAVLHRRATDPEGASAAAVSEVGAVSRESAGKGTGSRGVLWIPPV-------LQVPTPSP 74

  Fly   194 SNMDN--HHMHQGLLGKVEAGAAAFGGVYSRHPYDWPFNAVTHKEAASVNSGWWDMHSAAGSWLD 256
            ...|.  |.:....|..:..||        |..:     ....:||...::..::     .:|..
Mouse    75 GEGDGAPHLLAASALADLSCGA--------REDF-----REDSEEAPCASTSCFE-----PTWCS 121

  Fly   257 MGGAGMHSTMANYASENYSSALSHSLLGSGQHLLQDTYKSMLPGQGVGVGVGVGMGGFSLPHSSP 321
            ....|...|.|.:..|                 |.|.                        .||.
Mouse   122 SPTGGSEPTQAFFEDE-----------------LSDA------------------------ESSC 145

  Fly   322 SAAAAAAATAAAA----AGGSPQGGSPSTPSPRSQRRYAGRATCDCPNCQEAERLGPAGVHLRKK 382
            |.:|...|..|:.    :|..|:|...:.|:|.:...|..|            ::.||...
Mouse   146 SDSAILDAPEASEEPDDSGEVPEGPPGARPAPSTGPTYRRR------------QITPASKR---- 194

  Fly   383 NIHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFAC 447
              |.|...||.|.|.|:||||:|.|.|||||||.|:||.|.|:|||||||.||.|||||||||:|
Mouse   195 --HQCSFHGCNKAYYKSSHLKSHQRTHTGERPFSCDWLDCDKKFTRSDELARHYRTHTGEKRFSC 257

  Fly   448 PVCNKRFMRSDHLAKHVKTH 467
            |:|.|:|.|||||.||.:.|
Mouse   258 PLCPKQFSRSDHLTKHARRH 277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sp1	NP_001259388.1	SP6-9-like_N	50..386	CDD:411694	47/262 (18%)
		C2H2 Zn finger	390..409	CDD:275368	11/18 (61%)
		zf-H2C2_2	401..428	CDD:463886	18/26 (69%)
		C2H2 Zn finger	417..439	CDD:275368	15/21 (71%)
		zf-H2C2_2	431..454	CDD:463886	17/22 (77%)
		zf-C2H2	445..467	CDD:395048	13/21 (62%)
		C2H2 Zn finger	447..467	CDD:275368	12/19 (63%)
Klf14	NP_001128565.1	KLF14_N	2..196	CDD:409238	47/262 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	153..196		11/60 (18%)
		COG5048	198..>283	CDD:227381	54/80 (68%)
		C2H2 Zn finger	200..219	CDD:275368	11/18 (61%)
		C2H2 Zn finger	227..249	CDD:275368	15/21 (71%)
		C2H2 Zn finger	257..277	CDD:275368	12/19 (63%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	270..325		4/8 (50%)