DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sp1 and klf11b

DIOPT Version :9

Sequence 1:	NP_001259388.1	Gene:	Sp1 / 31913	FlyBaseID:	FBgn0020378	Length:	726	Species:	Drosophila melanogaster
Sequence 2:	NP_001071072.1	Gene:	klf11b / 559076	ZFINID:	ZDB-GENE-061103-82	Length:	458	Species:	Danio rerio

Alignment Length:	158	Identity:	72/158 - (45%)
Similarity:	88/158 - (55%)	Gaps:	39/158 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   339 PQGG----SPSTPSPRSQRRYAGRATCDCPNCQEAER---------LGPAGVHL----------- 379
            |||.    .|.:|...:|:            ||:...         |.||.|::
Zfish   276 PQGTVMFVMPQSPVSSTQQ------------CQQTVMTLGNTKLLPLAPAPVYVPSGQSSATQVD 328

  Fly   380 --RKKNIHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGE 442
              |::| :.|:.|||.|.|.|:||||||||.||||:||.|||..|.|:|.|||||.||.||||||
Zfish   329 FSRRRN-YVCNFPGCRKTYFKSSHLKAHLRTHTGEKPFSCNWEGCDKKFARSDELSRHRRTHTGE 392

  Fly   443 KRFACPVCNKRFMRSDHLAKHVKTHNGT 470
            |:|.||||.:||||||||.||.:.|..|
Zfish   393 KKFVCPVCERRFMRSDHLTKHARRHMTT 420

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sp1	NP_001259388.1	C2H2 Zn finger	390..409	CDD:275368	14/18 (78%)
		zf-H2C2_2	401..428	CDD:290200	19/26 (73%)
		C2H2 Zn finger	417..439	CDD:275368	14/21 (67%)
		zf-H2C2_2	431..454	CDD:290200	16/22 (73%)
		zf-C2H2	445..467	CDD:278523	15/21 (71%)
		C2H2 Zn finger	447..467	CDD:275368	14/19 (74%)
klf11b	NP_001071072.1	COG5048	334..>390	CDD:227381	37/56 (66%)
		C2H2 Zn finger	340..359	CDD:275368	14/18 (78%)
		zf-H2C2_2	351..378	CDD:290200	19/26 (73%)
		C2H2 Zn finger	367..389	CDD:275368	14/21 (67%)
		zf-H2C2_2	381..404	CDD:290200	16/22 (73%)
		zf-C2H2	395..417	CDD:278523	15/21 (71%)
		C2H2 Zn finger	397..417	CDD:275368	14/19 (74%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910