Protein Alignment Sp1 and klf4

DIOPT Version :10

• Sequence 1: NP_001259388.1
• Gene: Sp1 / 31913
• FlyBaseID: FBgn0020378
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: NP_001017280.1
• Gene: klf4 / 550034
• XenbaseID: XB-GENE-1015049
• Length: 407
• Species: Xenopus tropicalis
• Alignment Length: 374
• Identity: 108/374 - (28%)
• Similarity: 159/374 - (42%)
• Gaps: 39/374 - (10%)

  Fly   112 ISAASSSSSSGSSGGQSSRSLSSSASTMVNITASRPLASSCAAVGGGSTGSSSSASGSQSSSTAS 176
            :.::|||||..:|......:|..:.|.:.:.|.:......|.....|.|...::...:.||:|.:
 Frog    54 VGSSSSSSSVTASSPPPPATLPDTMSALSSTTCNFVYQVRCPQESSGGTLMYNARDPTMSSATFN 118

  Fly   177 AV----AAAYGGDLYFPNTSTSNMDNHHMHQ----GLLGKVEAGAAAFGGVY--------SRHPY 225
            ..    .:..||  :.......::|...|.|    .|.||.........|.|        :....
 Frog   119 LADINDVSPSGG--FVAELMRPDLDPVFMQQQPQASLQGKFVLKTTVSMGDYGQTISVRKNNSGI 181

  Fly   226 DWPFNAVTHKEAASVNSGWWDMHSAAGSWLDMGGAGMHS-TMANYASENYSSALSHSLLGSGQHL 289
            |.|.:..||:..........:..|:..|...|.|.|..| :|..:.              :|:.|
 Frog   182 DSPLSYTTHQLPRVCQKIKQEPSSSCTSACPMDGQGQQSQSMREFQ--------------AGRGL 232

  Fly   290 LQDTYKSMLPGQGVGVGVGVGMGGFSLPHSSPSAAAAAAATAAAAAGGSPQGGSPSTPSPRSQRR 354
            ...|.:|:.|.:  .:|........:|.|||.....|...:|:.:...|.|   |.|..|.:|.:
 Frog   233 PIRTNQSLSPEE--LMGRDCHSSSQTLSHSSLPIPPAYHTSASFSHFTSDQ---PQTQLPPTQLQ 292

  Fly   355 YAGRATC-DCPNCQEAERLGPAGVHLRKKNIHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCN 418
            |....|. .|...:...:.|......::...|:|...||||.|.|:||||||||.||||:|:.|:
 Frog   293 YQELLTTGGCIPEESKPKRGRKSWPRKRTATHTCEYAGCGKTYTKSSHLKAHLRTHTGEKPYHCD 357

  Fly   419 WLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLAKHVKTH 467
            |..||.:|.|||||.||.|.|||.:.|.|..|::.|.||||||.|:|.|
 Frog   358 WEGCGWKFARSDELTRHYRKHTGHRPFQCQRCDRAFSRSDHLALHMKRH 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sp1	NP_001259388.1	SP6-9-like_N	50..386	CDD:411694	58/291 (20%)
		C2H2 Zn finger	390..409	CDD:275368	14/18 (78%)
		zf-H2C2_2	401..428	CDD:463886	17/26 (65%)
		C2H2 Zn finger	417..439	CDD:275368	13/21 (62%)
		zf-H2C2_2	431..454	CDD:463886	11/22 (50%)
		zf-C2H2	445..467	CDD:395048	12/21 (57%)
		C2H2 Zn finger	447..467	CDD:275368	11/19 (58%)
klf4	NP_001017280.1	KLF4_N	1..324	CDD:409228	58/290 (20%)
		zf-C2H2	324..348	CDD:395048	16/23 (70%)
		C2H2 Zn finger	326..348	CDD:275368	15/21 (71%)
		zf-H2C2_2	340..367	CDD:463886	17/26 (65%)
		C2H2 Zn finger	356..378	CDD:275368	13/21 (62%)
		zf-H2C2_2	370..395	CDD:463886	12/24 (50%)
		C2H2 Zn finger	386..406	CDD:275368	11/19 (58%)