DRSC/TRiP Functional Genomics Resources

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Protein Alignment Sp1 and KLF13

DIOPT Version :9

Sequence 1:NP_001259388.1 Gene:Sp1 / 31913 FlyBaseID:FBgn0020378 Length:726 Species:Drosophila melanogaster
Sequence 2:NP_057079.2 Gene:KLF13 / 51621 HGNCID:13672 Length:288 Species:Homo sapiens


Alignment Length:257 Identity:95/257 - (36%)
Similarity:115/257 - (44%) Gaps:68/257 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   316 LPHSSPSAAAAAAATAAAAAGGSPQGGSPSTPSPRSQRRYAGRATCDCPNCQEAERLGPAGVHLR 380
            ||..:|. ..:..|..||||..||....|...:.....|..|.|....|..::..|.|.:...|.
Human    98 LPPPAPE-PTSPGAEGAAAAPPSPAWSEPEPEAGLEPEREPGPAGSGEPGLRQRVRRGRSRADLE 161

  Fly   381 K-KNIHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKR 444
            . :..|.||..||.|||||:||||||||.|||||||.|:|..|.|:|.|||||.||.|||||||:
Human   162 SPQRKHKCHYAGCEKVYGKSSHLKAHLRTHTGERPFACSWQDCNKKFARSDELARHYRTHTGEKK 226

  Fly   445 FACPVCNKRFMRSDHLAKHVKTHNGTANHQANGHNGGLKKGSSESCSDSEEAANQSGESNGLGGV 509
            |:||:|.|||||||||.||.:.|       ||.|.|.|::                         
Human   227 FSCPICEKRFMRSDHLTKHARRH-------ANFHPGMLQR------------------------- 259

  Fly   510 GSGPQTGGAGGGGGGSSSGNGAGTLAVSGSVTTGAGAGSGTGSSNSNSNSGGSSGSVSGSVS 571
                                              .|.||.|||.:..|.|..||.::|.:.|
Human   260 ----------------------------------RGGGSRTGSLSDYSRSDASSPTISPASS 287

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Sp1NP_001259388.1 C2H2 Zn finger 390..409 CDD:275368 15/18 (83%)
zf-H2C2_2 401..428 CDD:290200 19/26 (73%)
C2H2 Zn finger 417..439 CDD:275368 13/21 (62%)
zf-H2C2_2 431..454 CDD:290200 16/22 (73%)
zf-C2H2 445..467 CDD:278523 15/21 (71%)
C2H2 Zn finger 447..467 CDD:275368 14/19 (74%)
KLF13NP_057079.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 23..57
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 71..166 18/68 (26%)
COG5048 <162..252 CDD:227381 61/96 (64%)
zf-C2H2 167..191 CDD:278523 18/23 (78%)
C2H2 Zn finger 169..191 CDD:275368 17/21 (81%)
zf-H2C2_2 183..210 CDD:290200 19/26 (73%)
C2H2 Zn finger 199..221 CDD:275368 13/21 (62%)
zf-H2C2_2 213..236 CDD:290200 16/22 (73%)
zf-C2H2 227..249 CDD:278523 15/21 (71%)
C2H2 Zn finger 229..249 CDD:275368 14/19 (74%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 249..288 18/105 (17%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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