Protein Alignment Sp1 and sp7

DIOPT Version :9

• Sequence 1: NP_001259388.1
• Gene: Sp1 / 31913
• FlyBaseID: FBgn0020378
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: NP_998028.1
• Gene: sp7 / 405789
• ZFINID: ZDB-GENE-040629-2
• Length: 440
• Species: Danio rerio
• Alignment Length: 545
• Identity: 190/545 - (34%)
• Similarity: 238/545 - (43%)
• Gaps: 168/545 - (30%)

  Fly    46 TPLAMLAAQCNKLSNKSPPPLADAAVGKGFHPWKKSPNSPAAGSSGSSGGGGGGGGSSAGQHSPC 110
            :|||||.|.|||..:.|  |:.|:|          :|..|                   |...|.
Zfish    15 SPLAMLTATCNKFGSTS--PVRDSA----------TPGKP-------------------GSTIPI 48

  Fly   111 AISAASSSSSSGSSGGQSSRSLSSSASTMVNITASRPLASSCAAVGGGSTGSSSSASG--SQSSS 173
            ..:.:.:|....:..|::.                        :|....|||.||:.|  :.:.|
Zfish    49 KKAYSMTSELQSAKNGRNE------------------------SVADSYTGSFSSSGGLLTPTGS 89

  Fly   174 TASAVAAAYGGDLYFP----NTSTSNMDNHHMHQGLLG-KVEAGAAAFGGVY--SRHPYDWPFNA 231
            ...|...|||.: |.|    .||:.:.|     ..||| |..|........|  ..|||...:..
Zfish    90 PPPAPTGAYGSE-YNPFSTFQTSSVSQD-----PSLLGSKATADCLTSVNTYLDMTHPYGSWYKG 148

  Fly   232 VTH----KEAASVNSGWWDMHSAAGSWLDMGGAGMHSTM-------------------------- 266
            : |    ...|:..|.|||:|:.| :||..|.|...|..
Zfish   149 I-HPGITASPANATSSWWDVHTNA-NWLSPGQAQPDSLQAPLQPVAPQASLNPQMPSYTPDFTPL 211

  Fly   267 --ANYASENYSSALSHSLLGSGQHLL-QDTYKSMLPGQGVGVGVGVGMGGFSLPHSSPSAAAAAA 328
              |.|.|...||: || ||.|.||:| ||.||                     |...|::.....
Zfish   212 NPAPYPSVGLSSS-SH-LLQSSQHMLPQDMYK---------------------PKPVPTSGILDN 253

  Fly   329 ATAAAAAGGSPQGGSPSTPSPRSQRRYAGRATCDCPNCQEAERLGPAGVHLRKKNIHSCHIPGCG 393
            :....:|.||......:|          ||::||||||||.||||.:...||||.:|||||||||
Zfish   254 SMGLKSARGSGYAAGSTT----------GRSSCDCPNCQELERLGASAASLRKKPVHSCHIPGCG 308

  Fly   394 KVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSD 458
            |||||.|||||||||||||||||||||||||||||||||:||:||||.||:|.|.:|||||.|||
Zfish   309 KVYGKASHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELERHVRTHTREKKFTCLLCNKRFTRSD 373

  Fly   459 HLAKHVKTHNGTANHQANGHNGGLKKGSSESCSDSEEAANQSGESNGLGGVGSGPQTG---GAGG 520
            ||:||.|||                  |..|....||...::.||:......:|.:.|   .|.|
Zfish   374 HLSKHQKTH------------------SEASLQGKEEPETRAEESSADKVAPAGSEIGIQEPAVG 420

  Fly   521 GGGGSSSGNGAGTLAVSGSVTTGAG 545
            |...||:|||         |.:|:|
Zfish   421 GEEKSSTGNG---------VDSGSG 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sp1	NP_001259388.1	C2H2 Zn finger	390..409	CDD:275368	17/18 (94%)
		zf-H2C2_2	401..428	CDD:290200	26/26 (100%)
		C2H2 Zn finger	417..439	CDD:275368	19/21 (90%)
		zf-H2C2_2	431..454	CDD:290200	15/22 (68%)
		zf-C2H2	445..467	CDD:278523	15/21 (71%)
		C2H2 Zn finger	447..467	CDD:275368	14/19 (74%)
sp7	NP_998028.1	zf-C2H2	300..324	CDD:278523	22/23 (96%)
		zf-C2H2_8	302..386	CDD:292531	71/101 (70%)
		C2H2 Zn finger	305..324	CDD:275368	17/18 (94%)
		zf-H2C2_2	316..343	CDD:290200	26/26 (100%)
		C2H2 Zn finger	332..354	CDD:275368	19/21 (90%)
		zf-H2C2_2	346..371	CDD:290200	17/24 (71%)
		C2H2 Zn finger	362..382	CDD:275368	14/19 (74%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	132	1.000	Domainoid score	I5066
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D295820at33208
OrthoFinder	1	1.000	-	-		FOG0001688
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23235
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	7	6.980