Protein Alignment Sp1 and sp4

DIOPT Version :10

• Sequence 1: NP_001259388.1
• Gene: Sp1 / 31913
• FlyBaseID: FBgn0020378
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: XP_073786720.1
• Gene: sp4 / 387291
• ZFINID: ZDB-GENE-031202-3
• Length: 720
• Species: Danio rerio
• Alignment Length: 671
• Identity: 183/671 - (27%)
• Similarity: 244/671 - (36%)
• Gaps: 242/671 - (36%)

  Fly    46 TPLAMLAAQCNKLSNKSPPPLADA----------------------------AVGKGFHPWKKSP 82
            :|||:|||.|:|:........|.|                            ..|.|   |:...
Zfish    42 SPLALLAATCSKIGGVGAEGQAAAQQQIIIDPSQGLLQLQNPTQQLELVPAQLTGNG---WQIIA 103

  Fly    83 NSPA---------AGSSGSSGGGGGG------GGSSAGQHSPCAISAASSSSSSGS--------- 123
            .|||         ||::.:|.....|      |.::|.|.....|...:..:|||.
Zfish   104 TSPATATKDSIQQAGANAASSEAAAGRKVKAVGSNNAAQQQFQIIQVQNLPNSSGGIQYQVIPHL 168

  Fly   124 ----------------------------SGGQSSRSLSS-----SASTMVN-------------- 141
                                        |.|.:...|::     |||.:.|
Zfish   169 QTADGQQIQISPSNPAALSVQPEQIQLISTGNNQAILATPQRTGSASIVQNQTIPLQIRPSFPLQ 233

  Fly   142 ---------------------ITASRPLASSCAAVGGG--------------------------- 158
                                 :|.:.|:.::.|..||.
Zfish   234 LQTIQGTQAPMVTTLPINLGGVTLALPVINNVAGAGGSVQLLQSSDGSISNGNQLITTVTTSTAD 298

  Fly   159 STGSSSS---ASGSQS--------SSTASAVAAAYGGDLYFPNTSTSNMDNHHMHQG------LL 206
            |||||:|   |:||.|        .||.|.|:|....|.....|.::.:.:.....|      ::
Zfish   299 STGSSTSTTTATGSDSVVVTSADGLSTTSMVSAESPKDNEADLTQSNGLQSTSEQAGQIQQFQIV 363

  Fly   207 G---------------------KVEAGAA-----------AF---GGVYSRHPYDWPFNAVTHKE 236
            |                     :::.|..           ||   ..|..|.|...|...::.:.
Zfish   364 GHPVLQQIQIQSPQQQVVQGSIQIQPGQTLQPVQQNLQLQAFQNPAQVLIRTPTLTPSGQISWQT 428

  Fly   237 AASVNSGWWDMHSAAGSWLDMGGAGMHSTMANYASENYSSALSHSLL--GSGQHLLQDTYKSMLP 299
            ....|:|.....:.|......|| |..:.:|..........||.:.|  |||   :|....:.|.
Zfish   429 VQVQNAGMPQQLTLAPVASSAGG-GTFAQIAPLTLGGSPITLSAAQLPAGSG---VQTVNIAGLG 489

  Fly   300 GQGVGV-GVGVGMGGFSLPHSSPSAAAAAAATAAAAAGG-----SP-QGGSPSTPS-----PRSQ 352
            ..||.| ||.:.:.|..............:|......|.     || |.|...:||     |..:
Zfish   490 AAGVQVQGVPLTITGVQGQQQGQDGVKVQSAPVTVTVGNISNAVSPEQMGQVQSPSDQEGQPSKR 554

  Fly   353 RRYAGRATCDCPNCQEAERLGPAGVHLRKKNIHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVC 417
            .|   |..|.||||::.|  |.......||..|.||:.||||||||||||:||||||||||||||
Zfish   555 LR---RVACSCPNCRDGE--GRNNSDPSKKKQHVCHMEGCGKVYGKTSHLRAHLRWHTGERPFVC 614

  Fly   418 NWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLAKHVKTHNGTANHQANGHNGGL 482
            ||:|||||||||||||||.|||||||||.||.|:|||||||||:||:|||..
Zfish   615 NWIFCGKRFTRSDELQRHRRTHTGEKRFECPECSKRFMRSDHLSKHIKTHQN------------- 666

  Fly   483 KKGSSE----SCSDSEEAANQ 499
            |||.:.    :..:.||..::
Zfish   667 KKGGAALTIITTDEMEEEVDE 687

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sp1	NP_001259388.1	SP6-9-like_N	50..386	CDD:411694	103/548 (19%)
		C2H2 Zn finger	390..409	CDD:275368	16/18 (89%)
		zf-H2C2_2	401..428	CDD:463886	24/26 (92%)
		C2H2 Zn finger	417..439	CDD:275368	19/21 (90%)
		zf-H2C2_2	431..454	CDD:463886	18/22 (82%)
		zf-C2H2	445..467	CDD:395048	16/21 (76%)
		C2H2 Zn finger	447..467	CDD:275368	15/19 (79%)
sp4	XP_073786720.1	None