DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sp1 and CG42741

DIOPT Version :9

Sequence 1:	NP_001259388.1	Gene:	Sp1 / 31913	FlyBaseID:	FBgn0020378	Length:	726	Species:	Drosophila melanogaster
Sequence 2:	NP_611747.2	Gene:	CG42741 / 37654	FlyBaseID:	FBgn0261705	Length:	362	Species:	Drosophila melanogaster

Alignment Length:	395	Identity:	126/395 - (31%)
Similarity:	168/395 - (42%)	Gaps:	88/395 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 QHSPCAISAASSSSSSGSSGGQSSRSLSSSASTMVNITASRPLASSCAAVGGGSTGSSSSA---S 167
            |..|..:|..|..:|: |.|..||....|||:..|..:..:|         |||:|||||:   :
  Fly    23 QVEPVDLSLRSPRAST-SHGSSSSSYKFSSANKAVGYSNGKP---------GGSSGSSSSSGFGA 77

  Fly   168 GSQSSSTASAVAAAYGGDLYFPNTSTSNMDNHHMHQGLLGKVEAGAAAFGGVYSRHPYDWPFNAV 232
            ||..||:..|.||.....||                           |..|| |:.|:. ||.|.
  Fly    78 GSAGSSSLGAFAAQQQQQLY---------------------------ASSGV-SKLPFS-PFFAA 113

  Fly   233 -----THKEAASVNSGWWDMHSAAGSWLDMGGAGMHSTMA--NYASENYSSALSHSLLGSGQHLL 290
                 |::..:...||              .|.|..|...  |..|.:|::..|....||..:.:
  Fly   114 SPFFFTYRRISGSGSG--------------NGTGSVSVKQEDNNNSCSYNNGSSSGGAGSAANSM 164

  Fly   291 QDTYKSMLP-------------GQGVGVGVGVGMGGFSLP---HSSPSAAAAAAATAAAAA---- 335
            || |:|...             |.|.........||.|.|   :||||..:.|.:.:..||
  Fly   165 QD-YESKFSLLSLFKNPYKFAGGDGQASRKTSPTGGSSKPLASNSSPSWKSYAGSGSPHAALNPA 228

  Fly   336 -GGSPQGGSPSTPSPRSQRRYAGRATCDCPNCQEAERLGPAGVHLRKKN--IHSCHIPGCGKVYG 397
             ||..:|.:....|..|...:.|..:. ......::.:...|.:...||  :|.|...||.|||.
  Fly   229 FGGMGRGATRKDNSSFSGINFGGGGSA-FGFTTSSDSMANGGYNDLSKNRKVHKCDTEGCDKVYT 292

  Fly   398 KTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLAK 462
            |:||||||.|.||||:|:||.|..|..||.|||||.||.|.|||.|.|.|.:|.:.|.|||||:.
  Fly   293 KSSHLKAHKRTHTGEKPYVCTWEGCIWRFARSDELTRHYRKHTGVKPFRCQLCTRSFSRSDHLSL 357

  Fly   463 HVKTH 467
            |::.|
  Fly   358 HMRRH 362

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sp1	NP_001259388.1	C2H2 Zn finger	390..409	CDD:275368	13/18 (72%)
		zf-H2C2_2	401..428	CDD:290200	17/26 (65%)
		C2H2 Zn finger	417..439	CDD:275368	13/21 (62%)
		zf-H2C2_2	431..454	CDD:290200	12/22 (55%)
		zf-C2H2	445..467	CDD:278523	10/21 (48%)
		C2H2 Zn finger	447..467	CDD:275368	9/19 (47%)
CG42741	NP_611747.2	COG5048	<273..>352	CDD:227381	44/78 (56%)
		zf-C2H2	280..304	CDD:278523	15/23 (65%)
		C2H2 Zn finger	282..304	CDD:275368	14/21 (67%)
		zf-H2C2_2	296..>313	CDD:290200	12/16 (75%)
		C2H2 Zn finger	312..334	CDD:275368	13/21 (62%)
		zf-H2C2_2	326..351	CDD:290200	13/24 (54%)
		C2H2 Zn finger	342..362	CDD:275368	9/19 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455423
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23235
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940