DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sp1 and Sp6

DIOPT Version :9

Sequence 1:	NP_001259388.1	Gene:	Sp1 / 31913	FlyBaseID:	FBgn0020378	Length:	726	Species:	Drosophila melanogaster
Sequence 2:	NP_001102303.1	Gene:	Sp6 / 363672	RGDID:	1306768	Length:	376	Species:	Rattus norvegicus

Alignment Length:	348	Identity:	140/348 - (40%)
Similarity:	176/348 - (50%)	Gaps:	79/348 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   209 VEAGAAAFGGVYSR-------HPYDWPFNAVTHKEAASVNSGWWDMHSAAGSWLDM--------- 257
            :|:.:....|.:|:       |.|:..|.. ||  ..:.:..|||:|... ||:|:
  Rat    81 LESDSPLAPGPFSKLLQPDMSHHYESWFRP-TH--PGTEDGSWWDLHPGT-SWMDLPHTQGALTS 141

  Fly   258 -GGAG-MHSTMANYASENYSSA-----LSHSLL--GSGQHLLQDTYKSMLPGQGVGVGVGVGMGG 313
             |..| :...:..|..::...|     ..|.||  ..|||||.       |..|..|
  Rat   142 PGHPGALQPALGGYVGDHQLCAPPPHPHPHHLLPAAGGQHLLG-------PPDGAKV-------- 191

  Fly   314 FSLPHSSPSAAAAAAATAAAAAGGSPQGGSPSTPSPRSQRRYAGRATCDCPNCQEAERLG-PAGV 377
              |..::|.:....::..|||   .|:|...|.|      |.:|:..|.||||.|||||| |.|.
  Rat   192 --LEAAAPESQGLDSSLDAAA---RPKGSRRSVP------RSSGQTVCRCPNCLEAERLGAPCGP 245

  Fly   378 H-LRKKNIHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTG 441
            . .:||::|:||||||||.|.||||||||||||:|:||||||||||||||||||||||||:||||
  Rat   246 DGGKKKHLHNCHIPGCGKAYAKTSHLKAHLRWHSGDRPFVCNWLFCGKRFTRSDELQRHLQTHTG 310

  Fly   442 EKRFACPVCNKRFMRSDHLAKHVKTHNGTANHQANGHNGGLKKGSSESCSDSEEAANQSGESNGL 506
            .|:|.|.||::.||||||||||:|||.|                     :..|.||...||...
  Rat   311 TKKFPCAVCSRVFMRSDHLAKHMKTHEG---------------------AKEEAAAAAQGEGKA- 353

  Fly   507 GGVGSGPQTGGAGGGGGGSSSGN 529
            |||...|...|.....|.|:|.|
  Rat   354 GGVVESPGGKGKREAEGSSASSN 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sp1	NP_001259388.1	C2H2 Zn finger	390..409	CDD:275368	16/18 (89%)
		zf-H2C2_2	401..428	CDD:290200	24/26 (92%)
		C2H2 Zn finger	417..439	CDD:275368	20/21 (95%)
		zf-H2C2_2	431..454	CDD:290200	15/22 (68%)
		zf-C2H2	445..467	CDD:278523	15/21 (71%)
		C2H2 Zn finger	447..467	CDD:275368	14/19 (74%)
Sp6	NP_001102303.1	C2H2 Zn finger	259..278	CDD:275368	16/18 (89%)
		COG5048	<261..>336	CDD:227381	61/74 (82%)
		zf-H2C2_2	270..297	CDD:290200	24/26 (92%)
		C2H2 Zn finger	286..308	CDD:275368	20/21 (95%)
		zf-H2C2_2	300..323	CDD:290200	15/22 (68%)
		zf-C2H2	314..336	CDD:278523	15/21 (71%)
		C2H2 Zn finger	316..336	CDD:275368	14/19 (74%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23235
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010