Protein Alignment Sp1 and sp5a

DIOPT Version :10

• Sequence 1: NP_001259388.1
• Gene: Sp1 / 31913
• FlyBaseID: FBgn0020378
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: NP_851304.2
• Gene: sp5a / 353154
• ZFINID: ZDB-GENE-030430-2
• Length: 368
• Species: Danio rerio
• Alignment Length: 464
• Identity: 148/464 - (31%)
• Similarity: 190/464 - (40%)
• Gaps: 148/464 - (31%)

  Fly    34 PQVNPDHPSLRGTPLAMLAAQCNKLSN---KSPPPLA----DAAVG---KGFHPWKKSPNSPAAG 88
            |..:|::.  :.:|||:|||.||::.:   .:|....    |..:|   :.||||....|..:..
Zfish    21 PNSSPENS--KHSPLALLAATCNRIGHHHGSTPTDFIQVPYDTTLGSPSRIFHPWSNEANHQSTL 83

  Fly    89 SSGSSGGGGGGGGSSAGQHSPCAISAASSSSSSGSSGGQSSRSLSSSASTMVNITASRPLASSCA 153
            ||..|.|                :|:.|...||.:|..:...:..:..:...:.:..:.|..|..
Zfish    84 SSNPSFG----------------LSSKSHLQSSYASHHELPLTPPADPTYPYDFSPVKMLPCSMQ 132

  Fly   154 AVGGGSTGSSSSASGSQSSSTASAV-AAAYGGDLYFPNTSTSNMDNHH--MHQGLLGKVEAGAAA 215
            ::              ||:...:.| |..|......|....|.:..|.  :||
Zfish   133 SL--------------QSTCPPTYVPAVTYAAPAPIPPAMPSFVPGHSGLVHQ------------ 171

  Fly   216 FGGVYSRHPYDWPFNAVTHKEAASVNSG----WWDMHSAAGSWLDMGGAGMHSTMANYASENYSS 276
                              .:...|.|.|    ||.        |..|....||...:........
Zfish   172 ------------------QQRQLSPNPGEDIPWWS--------LQQGNPVAHSVHPHRFPIQRGL 210

  Fly   277 ALSHSLLGSGQHLLQDTYKSMLPGQGVGVGVGVGMGGFSLPHS-SPSAAAAAAATAAAAAGGSPQ 340
            .|.|:....        |::.:.               :|.|: ||.|.|
Zfish   211 VLGHTDFAQ--------YQTQIA---------------ALLHTKSPLATA--------------- 237

  Fly   341 GGSPSTPSPRSQRRYAGRATCDCPNCQEAERLGPAGVHLRKKNIHSCHIPGCGKVYGKTSHLKAH 405
                     |..||      |.|||||.:......|    ||..|.|||||||||||||||||||
Zfish   238 ---------RRCRR------CRCPNCQSSSSSDEPG----KKKQHICHIPGCGKVYGKTSHLKAH 283

  Fly   406 LRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLAKHVKTHNGT 470
            ||||:||||||||||||||.||||||||||||||||||||.||.|.||||||||||||||||.
Zfish   284 LRWHSGERPFVCNWLFCGKSFTRSDELQRHLRTHTGEKRFVCPDCCKRFMRSDHLAKHVKTHQ-- 346

  Fly   471 ANHQANGHN 479
             |.::..|:
Zfish   347 -NKKSKSHD 354

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sp1	NP_001259388.1	SP6-9-like_N	50..386	CDD:411694	64/353 (18%)
		C2H2 Zn finger	390..409	CDD:275368	18/18 (100%)
		zf-H2C2_2	401..428	CDD:463886	24/26 (92%)
		C2H2 Zn finger	417..439	CDD:275368	20/21 (95%)
		zf-H2C2_2	431..454	CDD:463886	19/22 (86%)
		zf-C2H2	445..467	CDD:395048	18/21 (86%)
		C2H2 Zn finger	447..467	CDD:275368	17/19 (89%)
sp5a	NP_851304.2	SP1-4_N	23..>44	CDD:425404	9/22 (41%)
		SP5_N	102..264	CDD:412096	43/270 (16%)
		C2H2 Zn finger	268..287	CDD:275368	18/18 (100%)
		zf-C2H2	293..317	CDD:395048	22/23 (96%)
		C2H2 Zn finger	295..317	CDD:275368	20/21 (95%)
		zf-H2C2_2	309..332	CDD:463886	19/22 (86%)
		C2H2 Zn finger	325..345	CDD:275368	17/19 (89%)