DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sp1 and sp5l

DIOPT Version :9

Sequence 1:	NP_001259388.1	Gene:	Sp1 / 31913	FlyBaseID:	FBgn0020378	Length:	726	Species:	Drosophila melanogaster
Sequence 2:	NP_919352.1	Gene:	sp5l / 324261	ZFINID:	ZDB-GENE-030131-2981	Length:	357	Species:	Danio rerio

Alignment Length:	384	Identity:	142/384 - (36%)
Similarity:	177/384 - (46%)	Gaps:	82/384 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   119 SSSGSSGGQSSRSLSSSASTMVNITASRPL------ASSCAAVGGGSTGSSSSASGSQSSSTASA 177
            |||..||..:...|:::.|......:..|.      |||...:.......:||.|..|.:.|..
Zfish    23 SSSPESGPNTLSFLATTCSQAWQEGSQLPYEGPVGSASSMFQLWSNDVAPNSSLSAHQMTFTVP- 86

  Fly   178 VAAAYGGDLYFPN----TSTSNMDNHHMHQGLLGKVEAGAAAFGGVYSRHPYDWPFNAVTHKEAA 238
                   .:.||:    |..|:..:||.|.                  .|.::.|........:|
Zfish    87 -------KMQFPSHMQPTLGSHSHHHHHHH------------------HHHHELPLTPPAEPPSA 126

  Fly   239 SVNSGWWDMHSAAGSWLDMGGAGMHSTMANYASENYSSALSHSLLGSGQHLLQDTYKSMLPGQGV 303
                     :|...|.:.|.|...:.|..|..|:|:.|.|.:.   ||        ::.|||.
Zfish   127 ---------YSFELSPVKMQGNAPYYTQHNAVSQNFPSFLQNP---SG--------RAHLPGG-- 169

  Fly   304 GVGVGVGMGGFSLP--HSSPSA---------AAAAAATAAAAAGGSPQGGSPSTPSPRSQRRYAG 357
              .|..|...:|||  :|:||.         ........||...|:.:|...||   |..||
Zfish   170 --HVEDGQQWWSLPQGNSAPSGHPFSLGRQLVLGHQPQIAALLQGTSKGLLSST---RRCRR--- 226

  Fly   358 RATCDCPNCQEAERLGPAGVHLRKKNIHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFC 422
               |.|||||.... |.|.:...||.:|.||||.|||||.||||||||||||.|||||:||||||
Zfish   227 ---CKCPNCQSTGN-GGAALEFGKKRLHICHIPDCGKVYKKTSHLKAHLRWHAGERPFICNWLFC 287

  Fly   423 GKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLAKHVKTHNGTANHQAN-GHNG 480
            ||.||||||||||||||||||||.|..|.|||||||||:||||||....:..:. .|:|
Zfish   288 GKSFTRSDELQRHLRTHTGEKRFGCQQCGKRFMRSDHLSKHVKTHQSRKSRSSQPPHSG 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sp1	NP_001259388.1	C2H2 Zn finger	390..409	CDD:275368	16/18 (89%)
		zf-H2C2_2	401..428	CDD:290200	23/26 (88%)
		C2H2 Zn finger	417..439	CDD:275368	20/21 (95%)
		zf-H2C2_2	431..454	CDD:290200	18/22 (82%)
		zf-C2H2	445..467	CDD:278523	16/21 (76%)
		C2H2 Zn finger	447..467	CDD:275368	15/19 (79%)
sp5l	NP_919352.1	C2H2 Zn finger	255..274	CDD:275368	16/18 (89%)
		zf-C2H2	280..304	CDD:278523	21/23 (91%)
		C2H2 Zn finger	282..304	CDD:275368	20/21 (95%)
		zf-H2C2_2	296..319	CDD:290200	18/22 (82%)
		C2H2 Zn finger	312..332	CDD:275368	15/19 (79%)
		zf-C2H2	312..332	CDD:278523	15/19 (79%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23235
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.010