DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sp1 and Klf15

DIOPT Version :9

Sequence 1:	NP_001259388.1	Gene:	Sp1 / 31913	FlyBaseID:	FBgn0020378	Length:	726	Species:	Drosophila melanogaster
Sequence 2:	NP_572185.1	Gene:	Klf15 / 31410	FlyBaseID:	FBgn0025679	Length:	311	Species:	Drosophila melanogaster

Alignment Length:	159	Identity:	60/159 - (37%)
Similarity:	77/159 - (48%)	Gaps:	40/159 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   317 PHSS---PSAAAAAAATAAAAAGGSPQGGSPSTPSPRSQRRYAGRATCDCPNCQEAERLGPAGVH 378
            |||.   |..:::           ||  ||..:.||                   ||.:.|....
  Fly   153 PHSEIFVPDRSSS-----------SP--GSSDSASP-------------------AEAVAPPSAL 185

  Fly   379 LRKKNI-----HSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRT 438
            ...:|.     :.|....|.|:|.|.:|||||||.|.||:|:||:|..|..||:|||||.||.|:
  Fly   186 QMSENAAGERGYLCTFGNCEKIYAKPAHLKAHLRRHLGEKPYVCSWPDCVWRFSRSDELARHKRS 250

  Fly   439 HTGEKRFACPVCNKRFMRSDHLAKHVKTH 467
            |:|.|.:.|..|:|.|.|||||.||.|.|
  Fly   251 HSGVKPYKCDYCSKCFARSDHLTKHRKVH 279

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sp1	NP_001259388.1	C2H2 Zn finger	390..409	CDD:275368	11/18 (61%)
		zf-H2C2_2	401..428	CDD:290200	17/26 (65%)
		C2H2 Zn finger	417..439	CDD:275368	13/21 (62%)
		zf-H2C2_2	431..454	CDD:290200	11/22 (50%)
		zf-C2H2	445..467	CDD:278523	12/21 (57%)
		C2H2 Zn finger	447..467	CDD:275368	12/19 (63%)
Klf15	NP_572185.1	zf-C2H2_8	199..278	CDD:292531	44/78 (56%)
		C2H2 Zn finger	203..221	CDD:275368	11/17 (65%)
		C2H2 Zn finger	229..251	CDD:275368	13/21 (62%)
		zf-H2C2_2	243..268	CDD:290200	12/24 (50%)
		C2H2 Zn finger	259..279	CDD:275368	12/19 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455426
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23235
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940