DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sp1 and Zfp367

DIOPT Version :9

Sequence 1:	NP_001259388.1	Gene:	Sp1 / 31913	FlyBaseID:	FBgn0020378	Length:	726	Species:	Drosophila melanogaster
Sequence 2:	NP_001012051.1	Gene:	Zfp367 / 306695	RGDID:	1307136	Length:	340	Species:	Rattus norvegicus

Alignment Length:	200	Identity:	64/200 - (32%)
Similarity:	90/200 - (45%)	Gaps:	38/200 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   296 SMLPGQGVGVGVGVGM-GGFSLPHSSPSAAAAAAATAAAAAGGSPQGGSPSTPSPRSQ---RRYA 356
            ::.||...|| |..|: ....||  :...|..::|:.||.:||..:..:.|..|...:   ||
  Rat    76 TLSPGAAGGV-VSAGLPAATELP--TLRGAPPSSASVAAVSGGEDEEEASSPDSGHLKDGIRR-- 135

  Fly   357 GRATCDCPNCQEAERLGPAGVHLRKKNIHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLF 421
            ||     |.......|...|.|...:  ..|:|  |.:|:.:...|:||.|.||||||::|::..
  Rat   136 GR-----PRADTVRDLINEGEHSSSR--IRCNI--CNRVFPREKSLQAHKRTHTGERPYLCDYPD 191

  Fly   422 CGKRFTRSDELQRHLRTHTGEKRFACPV--CNKRFMR------------------SDHLAKHVKT 466
            |||.|.:|.:|:.|.|.|||||.|.|..  |..||..                  :|.|:||..|
  Rat   192 CGKAFVQSGQLKTHQRLHTGEKPFVCSENGCLSRFTHANRHCPKHPYARLKREEPTDTLSKHQST 256

  Fly   467 HNGTA 471
            .|..|
  Rat   257 DNKAA 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sp1	NP_001259388.1	C2H2 Zn finger	390..409	CDD:275368	6/18 (33%)
		zf-H2C2_2	401..428	CDD:290200	15/26 (58%)
		C2H2 Zn finger	417..439	CDD:275368	9/21 (43%)
		zf-H2C2_2	431..454	CDD:290200	11/24 (46%)
		zf-C2H2	445..467	CDD:278523	9/41 (22%)
		C2H2 Zn finger	447..467	CDD:275368	8/39 (21%)
Zfp367	NP_001012051.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	96..140		15/52 (29%)
		COG5048	157..>230	CDD:227381	33/74 (45%)
		zf-C2H2	158..179	CDD:278523	8/22 (36%)
		C2H2 Zn finger	159..179	CDD:275368	8/21 (38%)
		zf-H2C2_2	171..198	CDD:290200	15/26 (58%)
		C2H2 Zn finger	187..209	CDD:275368	9/21 (43%)
		zf-H2C2_2	202..228	CDD:290200	13/25 (52%)
		C2H2 Zn finger	217..256	CDD:275368	8/38 (21%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	280..317
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000