Protein Alignment Sp1 and Klf1

DIOPT Version :10

• Sequence 1: NP_001259388.1
• Gene: Sp1 / 31913
• FlyBaseID: FBgn0020378
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: XP_006255316.1
• Gene: Klf1 / 304666
• RGDID: 1309398
• Length: 381
• Species: Rattus norvegicus
• Alignment Length: 242
• Identity: 83/242 - (34%)
• Similarity: 106/242 - (43%)
• Gaps: 62/242 - (25%)

  Fly   283 LGSGQHL--LQDTYKSMLPGQGVGVGVGVGMGGFSLPHSSPSAAAAA------AATAAAAAGGSP 339
            |||.:|.  ...|.:...|...|...:..|:...:.|..|.|.|.:|      |..|..||..:|
  Rat   144 LGSEEHAGWAHPTPRPPTPEPFVAPVLAPGLAPKAQPAFSESRAVSAGGFFPRAGLAVPAAPSAP 208

  Fly   340 QG---GSPST-PSPRSQRRY-------AGRATCDCP----NCQEAERLGPAGVHL---------- 379
            .|   |.|:. |:|:.|..:       |..|....|    ||     |||..|..
  Rat   209 YGLLSGYPALYPAPQYQGHFQLFRGLAAPSAGPTAPPSFLNC-----LGPGAVGTELGATAIAGD 268

  Fly   380 -------------------RKKNIHSCHIPGCGKVYGKTSHLKAHLRWHT-----GERPFVCNWL 420
                               :::..|:|...||||.|.|:||||||||.||     ||:|:.|:|.
  Rat   269 AGLSPGAAPPKRSRRTLAQKRQAAHTCGHEGCGKSYTKSSHLKAHLRTHTAPCPSGEKPYACSWD 333

  Fly   421 FCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLAKHVKTH 467
            .|..||.|||||.||.|.|||.:.|.|.:|.:.|.||||||.|:|.|
  Rat   334 GCNWRFARSDELTRHYRKHTGHRPFCCGLCPRAFSRSDHLALHMKRH 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sp1	NP_001259388.1	SP6-9-like_N	50..386	CDD:411694	33/154 (21%)
		C2H2 Zn finger	390..409	CDD:275368	14/18 (78%)
		zf-H2C2_2	401..428	CDD:463886	17/31 (55%)
		C2H2 Zn finger	417..439	CDD:275368	13/21 (62%)
		zf-H2C2_2	431..454	CDD:463886	11/22 (50%)
		zf-C2H2	445..467	CDD:395048	12/21 (57%)
		C2H2 Zn finger	447..467	CDD:275368	11/19 (58%)
Klf1	XP_006255316.1	KLF1_N	28..293	CDD:409227	33/153 (22%)
		COG5048	<297..>380	CDD:227381	47/82 (57%)
		C2H2 Zn finger	298..317	CDD:275368	14/18 (78%)
		C2H2 Zn finger	330..352	CDD:275368	13/21 (62%)
		C2H2 Zn finger	360..380	CDD:275368	11/19 (58%)