Protein Alignment Sp1 and Sp4

DIOPT Version :9

• Sequence 1: NP_001259388.1
• Gene: Sp1 / 31913
• FlyBaseID: FBgn0020378
• Length: 726
• Species: Drosophila melanogaster
• Sequence 2: NP_036893.1
• Gene: Sp4 / 25162
• RGDID: 3741
• Length: 783
• Species: Rattus norvegicus
• Alignment Length: 475
• Identity: 160/475 - (33%)
• Similarity: 202/475 - (42%)
• Gaps: 113/475 - (23%)

  Fly    98 GGGGSSAGQHSPCAISAASSSSSSGSSGGQ-------------SSRSLSSSASTMVNITASRPLA 149
            |||....||       ..::::.||:|.|.             |:...|.|:||....|||..|.
  Rat   275 GGGTGQVGQ-------PTTTTTDSGTSNGNQLVSTPTTSTAPASTMPESPSSSTTCTTTASTSLT 332

  Fly   150 SSCAAVGGGSTG--SSSSASGSQSSSTASAVAAAYGGDLYFPNTSTSN-MDNHHMHQGLLGKVE- 210
            ||...|....||  :|:|||.|:.:.......||...:....:...|| :.|.......|.:|:
  Rat   333 SSDTLVSSADTGQYASTSASSSERTIEEPQTPAATESEAQSSSQLQSNGIQNAQDQSNSLQQVQI 397

  Fly   211 AGAAAFGGVYSRHPYDWPFNAVTHKEAASVNSGWWDM---------------------------- 247
            .|......:..:.|......|:. .::..:.||....
  Rat   398 VGQPILQQIQIQQPQQQIIQAIP-PQSFQLQSGQTIQTIQQQPLQNVQLQAVNPTQVLIRAPTLT 461

  Fly   248 HSAAGSW-------------LDMGGAGMH-------------STMANYASENYSSA---LSHSLL 283
            .|...||             |.:..||:.             :|:|..|....:.|   |:.:.|
  Rat   462 PSGQISWQTVQVQNIQSLSNLQVQNAGLSQQLTITPVSSSGGTTLAQIAPVAVAGAPITLNTAQL 526

  Fly   284 GSGQHLLQDTYKSMLPGQGVGV-GVGV----------GMGGFSLPHS--SPSAAAAAAATAAAAA 335
            .|..: ||....:.|...||.| ||.|          |..|..:..:  :|...|......|...
  Rat   527 ASVPN-LQTVSVANLGAAGVQVQGVPVTITSVAGQQQGQDGVKVQQATIAPVTVAVGGIANATIG 590

  Fly   336 GGSP---------QGGSPSTPSPRSQRRYAGRATCDCPNCQEAERLGPAGVHLRKKNIHSCHIPG 391
            ..||         ||...|....:..:|.. |..|.||||:|.|  |.......||..|.|||.|
  Rat   591 AVSPDQLTQVHLQQGQQTSDAEVQPGKRLR-RVACSCPNCREGE--GRGSSEPGKKKQHVCHIEG 652

  Fly   392 CGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMR 456
            |||||||||||:||||||||||||:|||:|||||||||||||||.|||||||||.||.|:|||||
  Rat   653 CGKVYGKTSHLRAHLRWHTGERPFICNWMFCGKRFTRSDELQRHRRTHTGEKRFECPECSKRFMR 717

  Fly   457 SDHLAKHVKTH-----NGTA 471
            ||||:||||||     .|||
  Rat   718 SDHLSKHVKTHQNKKGGGTA 737

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sp1	NP_001259388.1	C2H2 Zn finger	390..409	CDD:275368	16/18 (89%)
		zf-H2C2_2	401..428	CDD:290200	23/26 (88%)
		C2H2 Zn finger	417..439	CDD:275368	19/21 (90%)
		zf-H2C2_2	431..454	CDD:290200	18/22 (82%)
		zf-C2H2	445..467	CDD:278523	17/21 (81%)
		C2H2 Zn finger	447..467	CDD:275368	16/19 (84%)
Sp4	NP_036893.1	C2H2 Zn finger	648..670	CDD:275368	19/21 (90%)
		COG5048	<661..732	CDD:227381	60/70 (86%)
		zf-H2C2_2	662..689	CDD:290200	23/26 (88%)
		C2H2 Zn finger	678..700	CDD:275368	19/21 (90%)
		zf-H2C2_2	692..715	CDD:290200	18/22 (82%)
		zf-C2H2	706..728	CDD:278523	17/21 (81%)
		C2H2 Zn finger	708..728	CDD:275368	16/19 (84%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23235
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010