DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sp1 and sptf-2

DIOPT Version :9

Sequence 1:	NP_001259388.1	Gene:	Sp1 / 31913	FlyBaseID:	FBgn0020378	Length:	726	Species:	Drosophila melanogaster
Sequence 2:	NP_495833.1	Gene:	sptf-2 / 188733	WormBaseID:	WBGene00011926	Length:	166	Species:	Caenorhabditis elegans

Alignment Length:	156	Identity:	76/156 - (48%)
Similarity:	96/156 - (61%)	Gaps:	13/156 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   315 SLPHSSPSAAAA-AAATAAAAAGGSPQGGSPSTPSPRSQRRYAGRATCDCPNCQEAERLGPAGVH 378
            |..||.||.:.. :.|:.:|::..|..|.:..|...|...|      |.|||| :|.:.|..|
Worm    17 SYHHSLPSISPPDSPASTSASSSSSSIGANELTTKRRKCER------CTCPNC-KAIKHGDRG-- 72

  Fly   379 LRKKNIHSCHIPGCGKVYGKTSHLKAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEK 443
              .::.|.|.:|||||.|.|||||:||||.|||:|||||:|..|||||.|||:|.||.||||.|.
Worm    73 --SQHTHLCSVPGCGKTYKKTSHLRAHLRKHTGDRPFVCDWFDCGKRFDRSDQLIRHKRTHTKEY 135

  Fly   444 RFACPVCNKRFMRSDHLAKHV-KTHN 468
            ||||..|.::|.|||||.:|: ..||
Worm   136 RFACKFCIRQFSRSDHLQQHLTSVHN 161

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sp1	NP_001259388.1	C2H2 Zn finger	390..409	CDD:275368	15/18 (83%)
		zf-H2C2_2	401..428	CDD:290200	20/26 (77%)
		C2H2 Zn finger	417..439	CDD:275368	14/21 (67%)
		zf-H2C2_2	431..454	CDD:290200	13/22 (59%)
		zf-C2H2	445..467	CDD:278523	11/22 (50%)
		C2H2 Zn finger	447..467	CDD:275368	9/20 (45%)
sptf-2	NP_495833.1	COG5048	<75..156	CDD:227381	53/80 (66%)
		C2H2 Zn finger	82..101	CDD:275368	15/18 (83%)
		C2H2 Zn finger	109..131	CDD:275368	14/21 (67%)
		C2H2 Zn finger	139..156	CDD:275368	8/16 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	44	1.000	Domainoid score	I8374
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14601
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR23235
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.010