DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Sp1 and Klf9

DIOPT Version :9

Sequence 1:NP_001259388.1 Gene:Sp1 / 31913 FlyBaseID:FBgn0020378 Length:726 Species:Drosophila melanogaster
Sequence 2:NP_034768.2 Gene:Klf9 / 16601 MGIID:1333856 Length:244 Species:Mus musculus


Alignment Length:260 Identity:96/260 - (36%)
Similarity:112/260 - (43%) Gaps:59/260 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   211 AGAAAFGGVYSRHPYDWPFNAVTHKEAASVNSGWWD---MHSAAGSWLDMGGAGMHSTMANYASE 272
            |.....||.........|...|| ||.......|.|   :.:.|.|.||:.         .|...
Mouse    22 AAVPEHGGAPEAERLRLPEREVT-KEHGDPGDTWKDYCTLVTIAKSLLDLN---------KYRPI 76

  Fly   273 NYSSALSHSLLGSGQHLLQDTYKSMLPGQGVGVGVGVGMGGFSLPHSSPSAAAAAAATAAAAAGG 337
            ...|..|.||..              |.:.:|....|.....|.|..||                
Mouse    77 QTPSVCSDSLES--------------PDEDIGSDSDVTTESGSSPSHSP---------------- 111

  Fly   338 SPQGGSPSTPSPRSQRRYAGRATCDCPNCQEAERLGPAGVHLRKKNIHSCHIPGCGKVYGKTSHL 402
            ..:..|.|.|||.| ..::|.|:              .|.|..:|. |.|...||||||||:|||
Mouse   112 EERQDSGSAPSPLS-LLHSGVAS--------------KGKHASEKR-HKCPYSGCGKVYGKSSHL 160

  Fly   403 KAHLRWHTGERPFVCNWLFCGKRFTRSDELQRHLRTHTGEKRFACPVCNKRFMRSDHLAKHVKTH 467
            |||.|.|||||||.|.|..|.|:|:|||||.||.|||||||:|.||:|.|||||||||.||.:.|
Mouse   161 KAHYRVHTGERPFPCTWPDCLKKFSRSDELTRHYRTHTGEKQFRCPLCEKRFMRSDHLTKHARRH 225

  Fly   468  467
            Mouse   226  225

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Sp1NP_001259388.1 C2H2 Zn finger 390..409 CDD:275368 15/18 (83%)
zf-H2C2_2 401..428 CDD:290200 18/26 (69%)
C2H2 Zn finger 417..439 CDD:275368 13/21 (62%)
zf-H2C2_2 431..454 CDD:290200 16/22 (73%)
zf-C2H2 445..467 CDD:278523 15/21 (71%)
C2H2 Zn finger 447..467 CDD:275368 14/19 (74%)
Klf9NP_034768.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 26..51 7/25 (28%)
COG5048 <78..234 CDD:227381 81/194 (42%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 79..143 22/109 (20%)
C2H2 Zn finger 145..167 CDD:275368 16/21 (76%)
C2H2 Zn finger 175..197 CDD:275368 13/21 (62%)
C2H2 Zn finger 205..225 CDD:275368 14/19 (74%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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